The most prominent historical example is Semmelweis, dude wanted doctors to start washing hands. Was ridiculed, bullied, and abused into insanity. I'll leave o

The most prominent historical example is Semmelweis, dude wanted doctors to start washing hands. Was ridiculed, bullied, and abused into insanity. I'll leave out mrna vaccines and gender related examples to avoid politically charged examples and people missing the forest for the trees. Here are some more. https://en.wikipedia.org/wiki/John_Abramson https://en.wikipedia.org/wiki/John_Abramson (Read his book!) https://en.wikipedia.org/wiki/Nancy_Olivieri https://en.wikipedia.org/wiki/Nancy_Olivieri https://en.wikipedia.org/wiki/David_Healy_(psychiatrist) https://en.wikipedia.org/wiki/David_Healy_(psychiatrist) https://en.wikipedia.org/wiki/Frances_Oldham_Kelsey https://en.wikipedia.org/wiki/Frances_Oldham_Kelsey You can google the general topic and see that there are hundreds more, but none of these individuals managed to become prominent or well known because they just gave up.