5 ms·

Like trying to treat his cancer with ivermectin? Doesn't seem to have worked.

tasuki 9mo ago
How many times did you have terminal cancer? My girlfriend died of cancer. She was 30 years old and we had a toddler. No matter how rational you start, terminal cancer diagnosis throws much rationality out the window.
- NoSalt 9mo ago
  I agree 100%. If I received a terminal cancer diagnosis, I would be willing to do almost anything to live longer.
  - BrandoElFollito 9mo ago
    I would not. At some point this becomes agony, this is the reason I have a suicide plan in place for a long time alredy, despite being in perfect health. It's not when you need it that you start googling around
    - tasuki 9mo ago
      FWIW, modern medicine is very good at making the pain go away, if you opt for it.
      - kstrauser 9mo ago
        So much this. They gave my mom an effectively unlimited supply of opiates when the time called for it, and we convinced her that it was perfectly OK and good to use them. One need not suffer without help, unless that happens to be personally important to them. Like, I can imagine religious objections, maybe, or perhaps an addict who wants to “go out clean” knowing that they beat the cravings. But if those don’t apply, pain meds are good and plentiful now.
      - BrandoElFollito 9mo ago
        Oh, this is not only a question of pain. For me it is more that I would not be my self anymore. People who put barriers for assisted suicide (like our politicians in France) are heartless bigots. Or did in other words - assholes.
- overfeed 9mo ago
  > No matter how rational you start, terminal cancer diagnosis throws much rationality out the window. Doctors who get cancer typically stay level-headed. I wish society talked about death and mortality more often and openly, most people are ill-equiped to face it square on, and yet its the one thing that is truly universal. Humanity needs sex-ed, but for dying.
  - bombcar 9mo ago
    > Humanity needs sex-ed, but for dying. I mean, we had that and threw it away; centuries of memento mori in various cultures and religions
  - hulitu 9mo ago
    > I wish society talked about death and mortality more often and openly, They do. For example "US army sunk a boat with drug traffickers, killing everyone." see Banality of evil https://en.wikipedia.org/wiki/Eichmann_in_Jerusalem https://en.wikipedia.org/wiki/Eichmann_in_Jerusalem
    - overfeed 9mo ago
      Use of passive voice doesn't help anyone grapple with one's mortality. I specifically meant in the context of contemplating our own mortality, and not that of others - which is closer to death porn and not death sex-ed (learning how to do it ourselves)
- kstrauser 9mo ago
  I am truly sorry for your loss. That must’ve been a nightmare, and I can imagine someone exploring outside their usual lines in such a situation. I hope you and your child are well now.
  - tasuki 9mo ago
    Thank you, yes we are well! Things have only been getting better for several years now :)
caminante 9mo ago
Snark aside, he got his doctor's approval first and acknowledged it didn't work after. Also, it shows promise in oncology, but doesn't have mature studies. [0] [0] https://cancerchoices.org/therapy/ivermectin/ https://cancerchoices.org/therapy/ivermectin/
- cthalupa 9mo ago
  I don't know that I would call en vitro studies promising. Cancer would be long be a solved problem if even a tenth of the stuff that kills cancer cells in a petri dish was viable in humans.
  - caminante 9mo ago
    It's not just *in vitro. Per article (and not arguing it's effective for human oncology), there are also studies with mice showing effectiveness.
    - gus_massa 9mo ago
      During peak covid-19 I read a lot of ivermectin studies posted in HN. Most were just horrible, with obvious mistakes. If you pick one, I can give a try to roast it.
      - caminante 9mo ago
        Fire away at the one in the link above.
        gus_massa 9mo ago
        I tried with 17: https://pmc.ncbi.nlm.nih.gov/articles/PMC7925581/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7925581/ From figure 1: > Complete tumor regression was observed in 6/15 mice on the combination treatment, 1/20 on ivermectin alone, 1/10 on anti-PD1 antibody alone, and 0/25 on no treatment. Ok, that looks interesting.
DanielleMolloy 9mo ago
He tried for a month, next to his regular treatments and then called Makis who is currently promoting it a quack.

How many times did you have terminal cancer? My girlfriend died of cancer. She was 30 years old and we had a toddler. No matter how rational you start, terminal cancer diagnosis throws much rationality out the window.

NoSalt 9mo ago
I agree 100%. If I received a terminal cancer diagnosis, I would be willing to do almost anything to live longer.
- BrandoElFollito 9mo ago
  I would not. At some point this becomes agony, this is the reason I have a suicide plan in place for a long time alredy, despite being in perfect health. It's not when you need it that you start googling around
  - tasuki 9mo ago
    FWIW, modern medicine is very good at making the pain go away, if you opt for it.
    - kstrauser 9mo ago
      So much this. They gave my mom an effectively unlimited supply of opiates when the time called for it, and we convinced her that it was perfectly OK and good to use them. One need not suffer without help, unless that happens to be personally important to them. Like, I can imagine religious objections, maybe, or perhaps an addict who wants to “go out clean” knowing that they beat the cravings. But if those don’t apply, pain meds are good and plentiful now.
    - BrandoElFollito 9mo ago
      Oh, this is not only a question of pain. For me it is more that I would not be my self anymore. People who put barriers for assisted suicide (like our politicians in France) are heartless bigots. Or did in other words - assholes.
overfeed 9mo ago
> No matter how rational you start, terminal cancer diagnosis throws much rationality out the window. Doctors who get cancer typically stay level-headed. I wish society talked about death and mortality more often and openly, most people are ill-equiped to face it square on, and yet its the one thing that is truly universal. Humanity needs sex-ed, but for dying.
- bombcar 9mo ago
  > Humanity needs sex-ed, but for dying. I mean, we had that and threw it away; centuries of memento mori in various cultures and religions
- hulitu 9mo ago
  > I wish society talked about death and mortality more often and openly, They do. For example "US army sunk a boat with drug traffickers, killing everyone." see Banality of evil https://en.wikipedia.org/wiki/Eichmann_in_Jerusalem https://en.wikipedia.org/wiki/Eichmann_in_Jerusalem
  - overfeed 9mo ago
    Use of passive voice doesn't help anyone grapple with one's mortality. I specifically meant in the context of contemplating our own mortality, and not that of others - which is closer to death porn and not death sex-ed (learning how to do it ourselves)
kstrauser 9mo ago
I am truly sorry for your loss. That must’ve been a nightmare, and I can imagine someone exploring outside their usual lines in such a situation. I hope you and your child are well now.
- tasuki 9mo ago
  Thank you, yes we are well! Things have only been getting better for several years now :)

caminante 9mo ago

Snark aside, he got his doctor's approval first and acknowledged it didn't work after. Also, it shows promise in oncology, but doesn't have mature studies. [0] [0] https://cancerchoices.org/therapy/ivermectin/ https://cancerchoices.org/therapy/ivermectin/

cthalupa 9mo ago
I don't know that I would call en vitro studies promising. Cancer would be long be a solved problem if even a tenth of the stuff that kills cancer cells in a petri dish was viable in humans.
- caminante 9mo ago
  It's not just *in vitro. Per article (and not arguing it's effective for human oncology), there are also studies with mice showing effectiveness.
  - gus_massa 9mo ago
    During peak covid-19 I read a lot of ivermectin studies posted in HN. Most were just horrible, with obvious mistakes. If you pick one, I can give a try to roast it.
    - caminante 9mo ago
      Fire away at the one in the link above.
      - gus_massa 9mo ago
        I tried with 17: https://pmc.ncbi.nlm.nih.gov/articles/PMC7925581/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7925581/ From figure 1: > Complete tumor regression was observed in 6/15 mice on the combination treatment, 1/20 on ivermectin alone, 1/10 on anti-PD1 antibody alone, and 0/25 on no treatment. Ok, that looks interesting.

DanielleMolloy 9mo ago

He tried for a month, next to his regular treatments and then called Makis who is currently promoting it a quack.