6 ms·

> Yogurt rose the most, followed by fresh fruit, nutrition bars and meat snacks. I would guess that this is because people are replacing full-blown meals with

> Yogurt rose the most, followed by fresh fruit, nutrition bars and meat snacks. I would guess that this is because people are replacing full-blown meals with smaller snacks. The meat snacks is probably because people are warned about losing muscle mass. Perhaps this affects yogurt consumption as well. > Notably, about one-third of users stopped taking the medication during the study period. This seems pretty high considering they're only following people for 6 months. I guess people are most likely to have side effects at the beginning, but I feel like I've not gotten the sense that a third of people bail within the first year, due to side effects or other reasons.

rumplecat 9mo ago
A common reason people quit is that they miss the pleasure that eating previously gave them.
- wincy 9mo ago
  I’ve lost 110 pounds on Zepbound and still absolutely love food. My relationship has changed with it substantially, though. I used to feel a strong urge to eat, often, and anything I could shovel down. I felt like I literally could never eat enough. I had terrible heartburn all the time. I’d eat a box of zebra cakes on the way home from the store. Something was very wrong with me. Right now I’m enjoying a homemade matzo ball soup with rotisserie chicken and homemade stock. It’s been absolutely life changing. I still eat zebra cakes sometimes, although far less, and I’m hard pressed to finish two, much less an entire box. I was able to lose weight before but it always required adhering strictly to a diet, or I’d just gain all the weight back. I’m so indescribably happy to be able to go on long bike rides, work on my house without getting tired after 20 minutes, and I go to the gym regularly. All this happened after the weight loss, not before. I think a lot of things we think are causing obesity is mixed up — the obesity for me seemed to be causing the dysfunction in almost every facet of my life.
  - rumplecat 9mo ago
    That's great it works for you. I was basing my comment on an article from a German newspaper that cites an obesity researcher who said that lost pleasure from eating is a major reason people quit: https://archive.ph/UnjMe https://archive.ph/UnjMe The evidence still appears anecdotal. They don't cite any studies that bear this out.
    - accidentallfact 9mo ago
      Most people quit, because it doesn't work: https://www.theguardian.com/wellness/2025/aug/14/ozempic-weight-loss https://www.theguardian.com/wellness/2025/aug/14/ozempic-wei... I hoped it will finally shut up those stuck on the dogma, but it seems the denial is far too strong, and nothing will change. And yes, it is a dogma, because no kind of evidence no matter how strong makes people like you reconsider.
      - hexbin010 9mo ago
        From your link: > “The meds are highly effective for a majority of patients but there is still a percentage who don’t lose a clinically significant percentage of body weight. Everyone’s physiology is a little different,” – Veronica Johnson MD, an obesity medicine specialist in Chicago > He explained that for someone who is overweight, shedding even a small amount of weight can improve heart and kidney function And, the Guardian is exactly the kind of outlet that would publish "woe is me, it doesn't work for me" stories, as it's their target audience. It's a tool - it can be a force multiplier if you also make other changes. If you just take the jab and do no exercise and continue eating bad, weight loss will be minimal. Yes it's been oversold – just like almost any other product/service that ha an advertising budget. That doesn't mean it "doesn't work" for everyone. Does your car 'not work' because you can't attract those extremely attractive ladies in the street which are often featured in the adverts?
        accidentallfact 9mo ago
        It also cites a study which says that the average loss is 5%. That isn't what most people imagine as "highly effective". Weight also doesn't tell the whole story. The people don't get any better, they get (more) starved in addition to staying obese. It's a disease with another cause, hunger is only a symptom. Too much money has been wasted on proving and "educating" people that it's just overeating, while there is an overwhelming amount of evidence to the contrary. The one that convinced me is horses. Horses get fat, and they need to wear a muzzle that makes eating difficult for them. Otherwise, they eat so much so fast that it literally kills them. There seem to be AREAS that are affected and areas that are less affected. Either there are fat people in the area, or there are no fat peoplle in the area. People who move seem to quickly change weight to fit the local norm. There doesn't seem to be any clear correlation with dietary habits, or anything else that is commonly observed. The entire Japan appears to be spared. It gets commonly missed that it isn't possible to get obese on purpose either. It's hard to eat more, and the body just seems to burn off the excess.
- newsclues 9mo ago
  That’s why I quit soylent. Now all I eat is chicken, and potatoes (regular and sweet) with avocado oil, and drink water. Salt is a bit of a problem because I use too much. Easy to lose weight or maintain it when you eat one meal a day ime
- hexbin010 9mo ago
  Yes, you need to find other pleasures in life. Use the clearer head space to figure out the emotional reasons for enjoying food so much. Or just spend a long time in the Netherlands and they can teach you how people who enjoy food are indulgent and weird and therefore bad.
mihaaly 9mo ago
I feel that analysing details and consequences based on the article is premature and marginal. The reduction of 5-8% of medication using households is barely beyond measurable (we have higher variation by the season). Yet they use the words 'striking', 'steep'. Also saying 'clear changes' in one part then admitting 'the reduction becomes smaller over time' (without specifics this time). The highest decrease of 10% for savory snacks is also modest at most (e.g. still consuming 9 pack instead of 10 in a reference period. having nothing good to watch on TV might have higher effect). The data might really be useful for the food industry once, but only after the usage of the medicine goes beyond 16% currently. 5-8% change, even 10%, for 16% of the population is tiny. To me the study sounds desperate to project significance, using adjectives rather than data for seeking attention.
- apparent 9mo ago
  Considering that only one person in a household might have gone on a medication, these percentages are actually more sizable than they might seem. It would have been useful if this were broken out differently, to highlight the different impact in single-person households and larger households.
protocolture 9mo ago
I get a lot of side effects on it, and during those side effects, yoghurt is about all I can stomach.

rumplecat 9mo ago

A common reason people quit is that they miss the pleasure that eating previously gave them.

wincy 9mo ago
I’ve lost 110 pounds on Zepbound and still absolutely love food. My relationship has changed with it substantially, though. I used to feel a strong urge to eat, often, and anything I could shovel down. I felt like I literally could never eat enough. I had terrible heartburn all the time. I’d eat a box of zebra cakes on the way home from the store. Something was very wrong with me. Right now I’m enjoying a homemade matzo ball soup with rotisserie chicken and homemade stock. It’s been absolutely life changing. I still eat zebra cakes sometimes, although far less, and I’m hard pressed to finish two, much less an entire box. I was able to lose weight before but it always required adhering strictly to a diet, or I’d just gain all the weight back. I’m so indescribably happy to be able to go on long bike rides, work on my house without getting tired after 20 minutes, and I go to the gym regularly. All this happened after the weight loss, not before. I think a lot of things we think are causing obesity is mixed up — the obesity for me seemed to be causing the dysfunction in almost every facet of my life.
- rumplecat 9mo ago
  That's great it works for you. I was basing my comment on an article from a German newspaper that cites an obesity researcher who said that lost pleasure from eating is a major reason people quit: https://archive.ph/UnjMe https://archive.ph/UnjMe The evidence still appears anecdotal. They don't cite any studies that bear this out.
  - accidentallfact 9mo ago
    Most people quit, because it doesn't work: https://www.theguardian.com/wellness/2025/aug/14/ozempic-weight-loss https://www.theguardian.com/wellness/2025/aug/14/ozempic-wei... I hoped it will finally shut up those stuck on the dogma, but it seems the denial is far too strong, and nothing will change. And yes, it is a dogma, because no kind of evidence no matter how strong makes people like you reconsider.
    - hexbin010 9mo ago
      From your link: > “The meds are highly effective for a majority of patients but there is still a percentage who don’t lose a clinically significant percentage of body weight. Everyone’s physiology is a little different,” – Veronica Johnson MD, an obesity medicine specialist in Chicago > He explained that for someone who is overweight, shedding even a small amount of weight can improve heart and kidney function And, the Guardian is exactly the kind of outlet that would publish "woe is me, it doesn't work for me" stories, as it's their target audience. It's a tool - it can be a force multiplier if you also make other changes. If you just take the jab and do no exercise and continue eating bad, weight loss will be minimal. Yes it's been oversold – just like almost any other product/service that ha an advertising budget. That doesn't mean it "doesn't work" for everyone. Does your car 'not work' because you can't attract those extremely attractive ladies in the street which are often featured in the adverts?
      - accidentallfact 9mo ago
        It also cites a study which says that the average loss is 5%. That isn't what most people imagine as "highly effective". Weight also doesn't tell the whole story. The people don't get any better, they get (more) starved in addition to staying obese. It's a disease with another cause, hunger is only a symptom. Too much money has been wasted on proving and "educating" people that it's just overeating, while there is an overwhelming amount of evidence to the contrary. The one that convinced me is horses. Horses get fat, and they need to wear a muzzle that makes eating difficult for them. Otherwise, they eat so much so fast that it literally kills them. There seem to be AREAS that are affected and areas that are less affected. Either there are fat people in the area, or there are no fat peoplle in the area. People who move seem to quickly change weight to fit the local norm. There doesn't seem to be any clear correlation with dietary habits, or anything else that is commonly observed. The entire Japan appears to be spared. It gets commonly missed that it isn't possible to get obese on purpose either. It's hard to eat more, and the body just seems to burn off the excess.
newsclues 9mo ago
That’s why I quit soylent. Now all I eat is chicken, and potatoes (regular and sweet) with avocado oil, and drink water. Salt is a bit of a problem because I use too much. Easy to lose weight or maintain it when you eat one meal a day ime
hexbin010 9mo ago
Yes, you need to find other pleasures in life. Use the clearer head space to figure out the emotional reasons for enjoying food so much. Or just spend a long time in the Netherlands and they can teach you how people who enjoy food are indulgent and weird and therefore bad.

mihaaly 9mo ago

I feel that analysing details and consequences based on the article is premature and marginal. The reduction of 5-8% of medication using households is barely beyond measurable (we have higher variation by the season). Yet they use the words 'striking', 'steep'. Also saying 'clear changes' in one part then admitting 'the reduction becomes smaller over time' (without specifics this time). The highest decrease of 10% for savory snacks is also modest at most (e.g. still consuming 9 pack instead of 10 in a reference period. having nothing good to watch on TV might have higher effect). The data might really be useful for the food industry once, but only after the usage of the medicine goes beyond 16% currently. 5-8% change, even 10%, for 16% of the population is tiny. To me the study sounds desperate to project significance, using adjectives rather than data for seeking attention.

apparent 9mo ago
Considering that only one person in a household might have gone on a medication, these percentages are actually more sizable than they might seem. It would have been useful if this were broken out differently, to highlight the different impact in single-person households and larger households.

protocolture 9mo ago

I get a lot of side effects on it, and during those side effects, yoghurt is about all I can stomach.