4 ms·

Other drugs aren't dosed in micrograms. It's pretty believable that street labs don't having the precision to get reliable dosing in such small quantities. 50

by jmalicki 10mo ago

Other drugs aren't dosed in micrograms. It's pretty believable that street labs don't having the precision to get reliable dosing in such small quantities. 50/100mcg is the typical ambulance dosing of fentanyl (where it's often used as the primary painkiller) - so at 500 times smaller than that of benadryl, it would take a reasonably high-end lab (at least by mid-level drug dealer standards) to not wildly mess up the dosing all the time - even if you mixed at larger scales, that still doesn't easily guarantee a uniform blend. It couldn't happen "just as easily" with any other drug.

fc417fc802 10mo ago
That's "pretty believable" but it's also complete bullshit. Why do you feel it necessary to comment in an authoritative manner when you don't know what you're talking about? It's literally spreading misinformation. The relevant technique is called "serial dilution" and it's regularly practiced in intro level chemistry and molecular biology classes. An otherwise untrained undergrad, using only a pipette and a volumetric flask, can consistently and reliably dilute samples to nanogram per liter levels. The error accumulates as some (exceedingly small) percentage of the target value per dilution step so even after 10 or more steps the error will remain well within manageable range. The issue is not fentanyl having a power level over 9000 or whatever other nonsense. It's people who don't know what they're doing, don't have access to a proper setup, and have no realistic way to implement a proper quality control regime manufacturing pharmaceuticals. Fentanyl didn't kill all these people. Objectively poor public policy indirectly led to the deaths of those who violated the law just as it did during prohibition.
- deleted 10mo ago
  [deleted]
- sheepscreek 10mo ago
  FYI DEA shares the stance around microdosing gone bad causing fatal overdose. This isn’t heresay. Perhaps you should read the links I shared in another comment.
herbst 10mo ago
LSD is an even smaller dose and I never heard of extremely strong LSD on the streets. Dealers manage to do their work properly.
- zipy124 10mo ago
  LSD is dropped onto paper in solution though. So to control dose is easy since you can easy halve a dose by doubling the volume of solution. Dosing a powder/crystal is much more difficult, especially if you need to get it back out of solution.
  - sva_ 10mo ago
    LSD is a powder/crystal (a salt). People just don't consume opioids orally, usually. There's something similar though: skin patches, since (other than LSD) fentanyl can be absorbed through the skin.
    - cap11235 10mo ago
      Blotters.
    - jmalicki 10mo ago
      In context, we're talking about pills cut with fentanyl, in which case it is often consumed orally, mixed in at a very small concentration compared to the other ingredients. Powedered drugs like cocaine mixed with fentanyl are even more horrible, since there is absolutely nothing to keep the concentration of fentanyl homogeneous throughout as it is handled.
  - herbst 10mo ago
    Fentanyl can be dropped onto a paper. As others said LSD is a salt, something will also dissolve fenta.

fc417fc802 10mo ago

That's "pretty believable" but it's also complete bullshit. Why do you feel it necessary to comment in an authoritative manner when you don't know what you're talking about? It's literally spreading misinformation. The relevant technique is called "serial dilution" and it's regularly practiced in intro level chemistry and molecular biology classes. An otherwise untrained undergrad, using only a pipette and a volumetric flask, can consistently and reliably dilute samples to nanogram per liter levels. The error accumulates as some (exceedingly small) percentage of the target value per dilution step so even after 10 or more steps the error will remain well within manageable range. The issue is not fentanyl having a power level over 9000 or whatever other nonsense. It's people who don't know what they're doing, don't have access to a proper setup, and have no realistic way to implement a proper quality control regime manufacturing pharmaceuticals. Fentanyl didn't kill all these people. Objectively poor public policy indirectly led to the deaths of those who violated the law just as it did during prohibition.

deleted 10mo ago
[deleted]
sheepscreek 10mo ago
FYI DEA shares the stance around microdosing gone bad causing fatal overdose. This isn’t heresay. Perhaps you should read the links I shared in another comment.

herbst 10mo ago

LSD is an even smaller dose and I never heard of extremely strong LSD on the streets. Dealers manage to do their work properly.

zipy124 10mo ago
LSD is dropped onto paper in solution though. So to control dose is easy since you can easy halve a dose by doubling the volume of solution. Dosing a powder/crystal is much more difficult, especially if you need to get it back out of solution.
- sva_ 10mo ago
  LSD is a powder/crystal (a salt). People just don't consume opioids orally, usually. There's something similar though: skin patches, since (other than LSD) fentanyl can be absorbed through the skin.
  - cap11235 10mo ago
    Blotters.
  - jmalicki 10mo ago
    In context, we're talking about pills cut with fentanyl, in which case it is often consumed orally, mixed in at a very small concentration compared to the other ingredients. Powedered drugs like cocaine mixed with fentanyl are even more horrible, since there is absolutely nothing to keep the concentration of fentanyl homogeneous throughout as it is handled.
- herbst 10mo ago
  Fentanyl can be dropped onto a paper. As others said LSD is a salt, something will also dissolve fenta.