3 ms·

Covid-19 leaves a lasting mark on the human brain

42 points by amichail 10mo ago

rippeltippel 10mo ago
The article doesn't say what those lasting marks are, nor their possible effects. Does anyone have any details on that?
- napkinartist 10mo ago
  They link to the paper in the article: https://www.sciencedirect.com/science/article/pii/S2666354625002005?via%3Dihub https://www.sciencedirect.com/science/article/pii/S266635462...
  - vizzier 10mo ago
    Still fairly non specific, as science probably should be (the question was if there visible MRI detectable changes, not what specific downstream changes were apparent) Interesting that if we can detect some of these changes with covid what other viruses might be doing to us up there.
    - euroderf 10mo ago
      This sounds a bit like the opening scene of something science fiction-ey dreadful. Like, even Pluribus.
stdclass 10mo ago
[flagged]
kazinator 10mo ago
> The NCNED brings together a critical mass of talented researchers and clinicians committed to improving the lives of the patients. Of course, improving the lives of patients for $$$! First you have to convince people that they have a problem, and their insurers that it's covered. It's the perfect disease. Scare people into suspecting they have it. All the hypochondriacs will believe it. It's difficult to measure and impossible to confirm recovery; you can milk that cow to kingdom come.
- defrost 10mo ago
  It's not US Pharma here, it's an Australian University (a country that actively works to keep health costs low and outcomes high) doing work funded by two outcomes orientated charities: * https://qbi.uq.edu.au/stafford-fox-medical-research-foundation https://qbi.uq.edu.au/stafford-fox-medical-research-foundati... * https://www.meresearch.org.uk/ https://www.meresearch.org.uk/ It's difficult to see a Martin Shkreli exploiting warped U.S. regulatory incentives parallel.
Frieren 10mo ago
> Our study identified altered signal intensity, abnormal tissue microstructure, and imbalanced neurochemicals in long COVID and COVID-19 recovered healthy controls. So, it seems that it has long lasting effects on everybody. The main difference is how severe are that effects. > Structural MRI studies have also identified alterations in brain morphology among COVID-RHC, including reductions in grey matter volume, thickness and global brain volume when compared with healthy controls That is scary. > Furthermore, long-term follow-up studies are crucial to determine whether the identified brain changes are progressive, stable or dynamic over time. This is interesting, thou. Is it permanent, it gets worse or better? That makes a big difference and it may also justify further studies and actions.
- krackers 10mo ago
  >Importantly, cognitive impairments are not limited to those with ongoing systemic symptoms; they are also evident in COVID-19 recovered individuals (COVID-RHC) who no longer report active symptoms, compared to healthy controls without SARS-CoV-2 infection (Non-COVID-HC) (Hampshire et al., 2021) The finding was done in 2021, it's not clear to me if it's an issue years out or it's just a manifestation of post-viral syndrome. Also today there are unlikely to be any people who haven't been infected by sars-cov2
  - fractallyte 10mo ago
    > Also today there are unlikely to be any people who haven't been infected by sars-cov2 We do exist... ;-)
    - throwaway290 10mo ago
      Most covid19 infections are asymptomatic so unless you treat every day you can't know;)
      - AstralStorm 10mo ago
        Well, even the antibody titre isn't foolproof (some people do not react or have their immune system later wiped). However having no antibody titre is pretty good sign you never had it. Not sure if there's a portable cheap blood test for it yet. Should be one, like for the active disease.
readthenotes1 10mo ago
Similar changes from taking the vaccine?

42 points by amichail 10mo ago

rippeltippel 10mo ago

The article doesn't say what those lasting marks are, nor their possible effects. Does anyone have any details on that?

napkinartist 10mo ago
They link to the paper in the article: https://www.sciencedirect.com/science/article/pii/S2666354625002005?via%3Dihub https://www.sciencedirect.com/science/article/pii/S266635462...
- vizzier 10mo ago
  Still fairly non specific, as science probably should be (the question was if there visible MRI detectable changes, not what specific downstream changes were apparent) Interesting that if we can detect some of these changes with covid what other viruses might be doing to us up there.
  - euroderf 10mo ago
    This sounds a bit like the opening scene of something science fiction-ey dreadful. Like, even Pluribus.

stdclass 10mo ago

[flagged]

kazinator 10mo ago

> The NCNED brings together a critical mass of talented researchers and clinicians committed to improving the lives of the patients. Of course, improving the lives of patients for $$$! First you have to convince people that they have a problem, and their insurers that it's covered. It's the perfect disease. Scare people into suspecting they have it. All the hypochondriacs will believe it. It's difficult to measure and impossible to confirm recovery; you can milk that cow to kingdom come.

defrost 10mo ago
It's not US Pharma here, it's an Australian University (a country that actively works to keep health costs low and outcomes high) doing work funded by two outcomes orientated charities: * https://qbi.uq.edu.au/stafford-fox-medical-research-foundation https://qbi.uq.edu.au/stafford-fox-medical-research-foundati... * https://www.meresearch.org.uk/ https://www.meresearch.org.uk/ It's difficult to see a Martin Shkreli exploiting warped U.S. regulatory incentives parallel.

Frieren 10mo ago

> Our study identified altered signal intensity, abnormal tissue microstructure, and imbalanced neurochemicals in long COVID and COVID-19 recovered healthy controls. So, it seems that it has long lasting effects on everybody. The main difference is how severe are that effects. > Structural MRI studies have also identified alterations in brain morphology among COVID-RHC, including reductions in grey matter volume, thickness and global brain volume when compared with healthy controls That is scary. > Furthermore, long-term follow-up studies are crucial to determine whether the identified brain changes are progressive, stable or dynamic over time. This is interesting, thou. Is it permanent, it gets worse or better? That makes a big difference and it may also justify further studies and actions.

krackers 10mo ago
>Importantly, cognitive impairments are not limited to those with ongoing systemic symptoms; they are also evident in COVID-19 recovered individuals (COVID-RHC) who no longer report active symptoms, compared to healthy controls without SARS-CoV-2 infection (Non-COVID-HC) (Hampshire et al., 2021) The finding was done in 2021, it's not clear to me if it's an issue years out or it's just a manifestation of post-viral syndrome. Also today there are unlikely to be any people who haven't been infected by sars-cov2
- fractallyte 10mo ago
  > Also today there are unlikely to be any people who haven't been infected by sars-cov2 We do exist... ;-)
  - throwaway290 10mo ago
    Most covid19 infections are asymptomatic so unless you treat every day you can't know;)
    - AstralStorm 10mo ago
      Well, even the antibody titre isn't foolproof (some people do not react or have their immune system later wiped). However having no antibody titre is pretty good sign you never had it. Not sure if there's a portable cheap blood test for it yet. Should be one, like for the active disease.

readthenotes1 10mo ago

Similar changes from taking the vaccine?