3 ms·

5 lbs a week is crazy? Are you expecting asymptotic approach to healthy weight? I'm 185 and would prefer to be more like 170, but 3 weeks seems too fast.

by blobbers 10mo ago

toomuchtodo 10mo ago
I started at 170lbs and my target is 135lbs (early 40s male). My blood panel looks good per my PCP, and as long as I'm not losing weight so fast I have excess skin or I experience liver, kidney, or pancreas failures of any degree, that meets my success criteria. I am trying to shed as much unhealthy visceral fat as possible while using the pharma intervention to dissuade me from unhealthy consumption habits. At $300/month cash pay through https://lilly.com https://lilly.com, I find the ROI to be exceptional.
- SoftTalker 10mo ago
  135lbs seems very low for an adult male. How tall are you? Why is that your target?
  - toomuchtodo 10mo ago
    While I think BMI is fairly suboptimal and would defer to a DEXA scan, that weight puts me right in the middle of a healthy BMI for a human of my gender, height, and age. As mentioned, I lift weights, three days per week. This also increases my metabolism and daily caloric budget (beyond basal and resting metabolic rates). My goal is to drop fat, gain muscle, and be strong with good cardio performance, and a GLP-1 turns off the part of my brain that made me carry excess unhealthy fat and eat the foods that made that fat. GLP-1s also promote thermogenesis, so it is turning on the switch to tell your body to burn fat that you would have to fast or get into ketosis via a ketogenic diet otherwise to get into (by first depleting your glycogen reserves). I do not get any fatigue such that I would when fasting or on a keto diet needed to encourage thermogenesis and burning up fat reserves, which is awesome imho. My brain says "you are fine" instead "you must eat, feel hungry, and get hangry, even though you already have all of this fat." A bug has been patched. https://pubmed.ncbi.nlm.nih.gov/?term=glp-1+thermogenesis https://pubmed.ncbi.nlm.nih.gov/?term=glp-1+thermogenesis (think like a hacker, the body is just another system to hack)
    - SoftTalker 10mo ago
      Interesting. I also do weightlifting 3x/week and my weight is in the 190s (male, 60yrs old, 6' tall). I am definitely carrying some excess fat but think my ideal would be somwhere around 175-180. Have never done any BMI tests.
  - JumpCrisscross 10mo ago
    > 135lbs seems very low for an adult male Impossible to characterize without height.
    - SoftTalker 10mo ago
      Well, that's why I asked how tall he was...
      - badc0ffee 10mo ago
        He said "right in the middle of a healthy BMI" which would make him 5'2" or 5'3".
mikepurvis 10mo ago
That's starvation level weight loss. A normal regime would be more like 1-2lbs per week via a moderate calorie deficit.
ceejayoz 10mo ago
> 5 lbs a week is crazy? https://www.nutrition.gov/topics/healthy-living-and-weight/strategies-success/interested-losing-weight https://www.nutrition.gov/topics/healthy-living-and-weight/s... "A reasonable rate of weight loss is 1 to 2 pounds per week." Going too fast has downsides. https://health.clevelandclinic.org/risks-of-losing-weight-too-fast https://health.clevelandclinic.org/risks-of-losing-weight-to...

5 lbs a week is crazy? Are you expecting asymptotic approach to healthy weight? I'm 185 and would prefer to be more like 170, but 3 weeks seems too fast.

toomuchtodo 10mo ago

I started at 170lbs and my target is 135lbs (early 40s male). My blood panel looks good per my PCP, and as long as I'm not losing weight so fast I have excess skin or I experience liver, kidney, or pancreas failures of any degree, that meets my success criteria. I am trying to shed as much unhealthy visceral fat as possible while using the pharma intervention to dissuade me from unhealthy consumption habits. At $300/month cash pay through https://lilly.com https://lilly.com, I find the ROI to be exceptional.

SoftTalker 10mo ago
135lbs seems very low for an adult male. How tall are you? Why is that your target?
- toomuchtodo 10mo ago
  While I think BMI is fairly suboptimal and would defer to a DEXA scan, that weight puts me right in the middle of a healthy BMI for a human of my gender, height, and age. As mentioned, I lift weights, three days per week. This also increases my metabolism and daily caloric budget (beyond basal and resting metabolic rates). My goal is to drop fat, gain muscle, and be strong with good cardio performance, and a GLP-1 turns off the part of my brain that made me carry excess unhealthy fat and eat the foods that made that fat. GLP-1s also promote thermogenesis, so it is turning on the switch to tell your body to burn fat that you would have to fast or get into ketosis via a ketogenic diet otherwise to get into (by first depleting your glycogen reserves). I do not get any fatigue such that I would when fasting or on a keto diet needed to encourage thermogenesis and burning up fat reserves, which is awesome imho. My brain says "you are fine" instead "you must eat, feel hungry, and get hangry, even though you already have all of this fat." A bug has been patched. https://pubmed.ncbi.nlm.nih.gov/?term=glp-1+thermogenesis https://pubmed.ncbi.nlm.nih.gov/?term=glp-1+thermogenesis (think like a hacker, the body is just another system to hack)
  - SoftTalker 10mo ago
    Interesting. I also do weightlifting 3x/week and my weight is in the 190s (male, 60yrs old, 6' tall). I am definitely carrying some excess fat but think my ideal would be somwhere around 175-180. Have never done any BMI tests.
- JumpCrisscross 10mo ago
  > 135lbs seems very low for an adult male Impossible to characterize without height.
  - SoftTalker 10mo ago
    Well, that's why I asked how tall he was...
    - badc0ffee 10mo ago
      He said "right in the middle of a healthy BMI" which would make him 5'2" or 5'3".

mikepurvis 10mo ago

That's starvation level weight loss. A normal regime would be more like 1-2lbs per week via a moderate calorie deficit.

ceejayoz 10mo ago

> 5 lbs a week is crazy? https://www.nutrition.gov/topics/healthy-living-and-weight/strategies-success/interested-losing-weight https://www.nutrition.gov/topics/healthy-living-and-weight/s... "A reasonable rate of weight loss is 1 to 2 pounds per week." Going too fast has downsides. https://health.clevelandclinic.org/risks-of-losing-weight-too-fast https://health.clevelandclinic.org/risks-of-losing-weight-to...