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But CBD does not need heat to convert. I have a hypothesis that taking cannabis (and especially CBD) out of our food chain may be contributing to the increase¹

by joquarky 10mo ago

But CBD does not need heat to convert. I have a hypothesis that taking cannabis (and especially CBD) out of our food chain may be contributing to the increase¹ in prevalence of chronic pain. ¹ https://pmc.ncbi.nlm.nih.gov/articles/PMC12588185/?utm_source=chatgpt.com https://pmc.ncbi.nlm.nih.gov/articles/PMC12588185/?utm_sourc...

jbkkd 10mo ago
When was cannabis ever in the human food chain?
- 5-0 10mo ago
  While not being cannabis, breast milk contains endocannabinoids.
- joquarky 10mo ago
  Livestock used to eat cannabis back when it was a weed.
TheGoddessInari 10mo ago
THC comes in a plant in the THCa form. CBD comes in CBDa form. Both are not bioactive by default in their natural form.
- horsawlarway 10mo ago
  All I'll say is go spend a day picking hops without gloves. There are a large number of cannabinoids at play, some clearly (as in observably and demonstrably) are bioactive in their natural, unheated form. --- None of which is said to endorse the other theory. Just to point out that claiming heat is required is incorrect.
  - mothballed 10mo ago
    The farm bill makes 'hemp' anything with below 0.3% THC legal. For this reason, we have a LOT of testing on the THC content of cannabis, since it is required to sell and manufacture. As it turns out, naturally cannabis quite commonly has >0.3% THC even before heating or activation of THCa. Any human-like animal with our receptors eating a large amount would get high as fuck, cooked or not. A ruminant eating pounds of the stuff raw, would not be that different from a human consuming an ounce of baked pot.
    - shdjhdfh 10mo ago
      This was killed in the recent budget bill: https://www.cnbc.com/2025/11/13/congress-thc-hemp-ban.html https://www.cnbc.com/2025/11/13/congress-thc-hemp-ban.html
- heavyset_go 10mo ago
  Both degrade into actives over time or exposure to air/sun/warmth, and then into CBN, which is itself active.

jbkkd 10mo ago

When was cannabis ever in the human food chain?

5-0 10mo ago
While not being cannabis, breast milk contains endocannabinoids.
joquarky 10mo ago
Livestock used to eat cannabis back when it was a weed.

TheGoddessInari 10mo ago

THC comes in a plant in the THCa form. CBD comes in CBDa form. Both are not bioactive by default in their natural form.

horsawlarway 10mo ago
All I'll say is go spend a day picking hops without gloves. There are a large number of cannabinoids at play, some clearly (as in observably and demonstrably) are bioactive in their natural, unheated form. --- None of which is said to endorse the other theory. Just to point out that claiming heat is required is incorrect.
- mothballed 10mo ago
  The farm bill makes 'hemp' anything with below 0.3% THC legal. For this reason, we have a LOT of testing on the THC content of cannabis, since it is required to sell and manufacture. As it turns out, naturally cannabis quite commonly has >0.3% THC even before heating or activation of THCa. Any human-like animal with our receptors eating a large amount would get high as fuck, cooked or not. A ruminant eating pounds of the stuff raw, would not be that different from a human consuming an ounce of baked pot.
  - shdjhdfh 10mo ago
    This was killed in the recent budget bill: https://www.cnbc.com/2025/11/13/congress-thc-hemp-ban.html https://www.cnbc.com/2025/11/13/congress-thc-hemp-ban.html
heavyset_go 10mo ago
Both degrade into actives over time or exposure to air/sun/warmth, and then into CBN, which is itself active.