4 ms·

But cannabis the needs heat to convert, it’s more likely it evolved with Human influence considering the years of overlapping land races tied to our trade route

But cannabis the needs heat to convert, it’s more likely it evolved with Human influence considering the years of overlapping land races tied to our trade routes

joquarky 9mo ago
But CBD does not need heat to convert. I have a hypothesis that taking cannabis (and especially CBD) out of our food chain may be contributing to the increase¹ in prevalence of chronic pain. ¹ https://pmc.ncbi.nlm.nih.gov/articles/PMC12588185/?utm_source=chatgpt.com https://pmc.ncbi.nlm.nih.gov/articles/PMC12588185/?utm_sourc...
- jbkkd 9mo ago
  When was cannabis ever in the human food chain?
  - 5-0 9mo ago
    While not being cannabis, breast milk contains endocannabinoids.
  - joquarky 9mo ago
    Livestock used to eat cannabis back when it was a weed.
- TheGoddessInari 9mo ago
  THC comes in a plant in the THCa form. CBD comes in CBDa form. Both are not bioactive by default in their natural form.
  - horsawlarway 9mo ago
    All I'll say is go spend a day picking hops without gloves. There are a large number of cannabinoids at play, some clearly (as in observably and demonstrably) are bioactive in their natural, unheated form. --- None of which is said to endorse the other theory. Just to point out that claiming heat is required is incorrect.
    - mothballed 9mo ago
      The farm bill makes 'hemp' anything with below 0.3% THC legal. For this reason, we have a LOT of testing on the THC content of cannabis, since it is required to sell and manufacture. As it turns out, naturally cannabis quite commonly has >0.3% THC even before heating or activation of THCa. Any human-like animal with our receptors eating a large amount would get high as fuck, cooked or not. A ruminant eating pounds of the stuff raw, would not be that different from a human consuming an ounce of baked pot.
      - shdjhdfh 9mo ago
        This was killed in the recent budget bill: https://www.cnbc.com/2025/11/13/congress-thc-hemp-ban.html https://www.cnbc.com/2025/11/13/congress-thc-hemp-ban.html
  - heavyset_go 9mo ago
    Both degrade into actives over time or exposure to air/sun/warmth, and then into CBN, which is itself active.
Aloisius 9mo ago
THCa in cannabis plants is unstable. It will slowly convert to THC as it dries even at room temperature.

But cannabis the needs heat to convert, it’s more likely it evolved with Human influence considering the years of overlapping land races tied to our trade routes

joquarky 9mo ago

But CBD does not need heat to convert. I have a hypothesis that taking cannabis (and especially CBD) out of our food chain may be contributing to the increase¹ in prevalence of chronic pain. ¹ https://pmc.ncbi.nlm.nih.gov/articles/PMC12588185/?utm_source=chatgpt.com https://pmc.ncbi.nlm.nih.gov/articles/PMC12588185/?utm_sourc...

jbkkd 9mo ago
When was cannabis ever in the human food chain?
- 5-0 9mo ago
  While not being cannabis, breast milk contains endocannabinoids.
- joquarky 9mo ago
  Livestock used to eat cannabis back when it was a weed.
TheGoddessInari 9mo ago
THC comes in a plant in the THCa form. CBD comes in CBDa form. Both are not bioactive by default in their natural form.
- horsawlarway 9mo ago
  All I'll say is go spend a day picking hops without gloves. There are a large number of cannabinoids at play, some clearly (as in observably and demonstrably) are bioactive in their natural, unheated form. --- None of which is said to endorse the other theory. Just to point out that claiming heat is required is incorrect.
  - mothballed 9mo ago
    The farm bill makes 'hemp' anything with below 0.3% THC legal. For this reason, we have a LOT of testing on the THC content of cannabis, since it is required to sell and manufacture. As it turns out, naturally cannabis quite commonly has >0.3% THC even before heating or activation of THCa. Any human-like animal with our receptors eating a large amount would get high as fuck, cooked or not. A ruminant eating pounds of the stuff raw, would not be that different from a human consuming an ounce of baked pot.
    - shdjhdfh 9mo ago
      This was killed in the recent budget bill: https://www.cnbc.com/2025/11/13/congress-thc-hemp-ban.html https://www.cnbc.com/2025/11/13/congress-thc-hemp-ban.html
- heavyset_go 9mo ago
  Both degrade into actives over time or exposure to air/sun/warmth, and then into CBN, which is itself active.

Aloisius 9mo ago

THCa in cannabis plants is unstable. It will slowly convert to THC as it dries even at room temperature.