3 ms·
Cancers aren't perfectly optimized to metastasize, and metasteses (rather than, e.g., bulk pressure from the original tumor) are usually what kills you. It's pe
by jessriedel 9mo ago
Cancers aren't perfectly optimized to metastasize, and metasteses (rather than, e.g., bulk pressure from the original tumor) are usually what kills you. It's perfectly possible that the procedure kills 90% or 99% of the cells in the original tumor but increases migration of the remaining cells such that the net effect reduces patient survival.
- elcritch 9mo agoDon't cancer metastases have more to do with cancer mutations allowing the cancer cells to form new tumors? Some cancer types tend do not develop the ability to colonize new tumors while others do regularly.
- jessriedel 9mo agoIt's quite a bit about that, but it doesn't detract from my point. Mechanical disturbance alone can spread cancer and increase mortality. "The risk of tumor seeding after liver biopsy is 2.7%" https://easl.eu/wp-content/uploads/2018/10/Hepatocellular-Carcinoma-English-Report.pdf https://easl.eu/wp-content/uploads/2018/10/Hepatocellular-Ca... Tissue containment systems for uterine morcellation https://www.fda.gov/medical-devices/safety-communications/update-perform-only-contained-morcellation-when-laparoscopic-power-morcellation-appropriate-fda https://www.fda.gov/medical-devices/safety-communications/up...