What are the downsides to this stuff? I don't know of any downsides to 7-Keto (7-oxo). However, I know that DHEA, on the other hand, has many downsides. It is

What are the downsides to this stuff? I don't know of any downsides to 7-Keto (7-oxo). However, I know that DHEA, on the other hand, has many downsides. It is important to note that 7-Keto (7-oxo) is not DHEA. It is a metabolite of DHEA. For a complete list of studies and abstracts, including the latest, I would search PubMed: http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=7-keto+dhea http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=... (7-Keto search; 14 hits.) http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=7-oxo+dhea http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=... (7-oxo search; 47 hits.) There was an LEF (Life Extension Foundation) magazine cover story on 7-Keto (7-oxo) in the May 2005 issue: http://www.lef.org/magazine/mag2005/may2005_cover_keto_01.htm http://www.lef.org/magazine/mag2005/may2005_cover_keto_01.ht... Scientists have documented DHEA’s wide-ranging benefits in numerous clinical studies. DHEA helps to retard the effects of aging and promotes enhanced longevity, exerting a multitude of effects through its conversion to some 150 metabolites, each with unique actions within the body. One of the most important of these is 7-Keto DHEA (commonly referred to as 7-Keto), a hormone metabolite that can safely boost immune function and help reduce body fat. Unlike DHEA, however, 7-Keto does not convert to estrogen and testosterone. Because DHEA and 7-Keto have separate and unique functions and properties, it is important to understand the differences between these two popular dietary supplements. [...] A study with mice suggests that 7-Keto can boost memory as well.17 In this experiment, researchers at the University of Wisconsin in Madison trained young mice in the use of a water maze. They found that a single injection of 7-Keto (at 24 mg/kg of body weight) reversed experimentally induced memory loss. The scientists then fed 7-Keto or DHEA to old mice that had learned the maze. They discovered that memory of the water-maze training was retained during a four-week test period in the mice receiving 7-Keto but not in those treated with DHEA. The article includes 18 references.