3 ms·

What are the downsides to this stuff? I googled a bit and couldn't find anything particularly detrimental. It even seems have "memory enhancement" attributed to

What are the downsides to this stuff? I googled a bit and couldn't find anything particularly detrimental. It even seems have "memory enhancement" attributed to it. http://www.delano.com/Articles/ketoDHEA.html http://www.delano.com/Articles/ketoDHEA.html - this was the most informative page that I could find discussing the benefits and claims against it. Seems to come out on top as being safe and effective though.

gravitycop 18y ago
What are the downsides to this stuff? I don't know of any downsides to 7-Keto (7-oxo). However, I know that DHEA, on the other hand, has many downsides. It is important to note that 7-Keto (7-oxo) is not DHEA. It is a metabolite of DHEA. For a complete list of studies and abstracts, including the latest, I would search PubMed: http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=7-keto+dhea http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=... (7-Keto search; 14 hits.) http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=7-oxo+dhea http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=... (7-oxo search; 47 hits.) There was an LEF (Life Extension Foundation) magazine cover story on 7-Keto (7-oxo) in the May 2005 issue: http://www.lef.org/magazine/mag2005/may2005_cover_keto_01.htm http://www.lef.org/magazine/mag2005/may2005_cover_keto_01.ht... Scientists have documented DHEA’s wide-ranging benefits in numerous clinical studies. DHEA helps to retard the effects of aging and promotes enhanced longevity, exerting a multitude of effects through its conversion to some 150 metabolites, each with unique actions within the body. One of the most important of these is 7-Keto DHEA (commonly referred to as 7-Keto), a hormone metabolite that can safely boost immune function and help reduce body fat. Unlike DHEA, however, 7-Keto does not convert to estrogen and testosterone. Because DHEA and 7-Keto have separate and unique functions and properties, it is important to understand the differences between these two popular dietary supplements. [...] A study with mice suggests that 7-Keto can boost memory as well.17 In this experiment, researchers at the University of Wisconsin in Madison trained young mice in the use of a water maze. They found that a single injection of 7-Keto (at 24 mg/kg of body weight) reversed experimentally induced memory loss. The scientists then fed 7-Keto or DHEA to old mice that had learned the maze. They discovered that memory of the water-maze training was retained during a four-week test period in the mice receiving 7-Keto but not in those treated with DHEA. The article includes 18 references.
gravitycop 18y ago
What are the downsides to this stuff? Here is one of the latest studies I could find (2007 Sep;18): http://www.ncbi.nlm.nih.gov/pubmed/17418559 http://www.ncbi.nlm.nih.gov/pubmed/17418559 This study tested the hypothesis that 3-acetyl-7-oxo-dehydroepiandrosterone alone (7-Keto) and in combination with calcium citrate, green tea extract, ascorbic acid, chromium nicotinate and cholecalciferol (HUM5007) will increase the resting metabolic rate (RMR) of overweight subjects maintained on a calorie-restricted diet. [...] In this study, the administration of HUM5007 or 7-Keto reversed the decrease in RMR normally associated with dieting. HUM5007 and 7-Keto increased RMR above basal levels and may benefit obese individuals with impaired energy expenditure. HUM5007 and 7-Keto were generally well tolerated and no serious adverse events were reported. Note that it says, "7-Keto [was] generally well tolerated and no serious adverse events were reported". Cholecalciferol is also known as Vitamin D3 and is widely available as a dietary supplement.

gravitycop 18y ago

What are the downsides to this stuff? I don't know of any downsides to 7-Keto (7-oxo). However, I know that DHEA, on the other hand, has many downsides. It is important to note that 7-Keto (7-oxo) is not DHEA. It is a metabolite of DHEA. For a complete list of studies and abstracts, including the latest, I would search PubMed: http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=7-keto+dhea http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=... (7-Keto search; 14 hits.) http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=7-oxo+dhea http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&term=... (7-oxo search; 47 hits.) There was an LEF (Life Extension Foundation) magazine cover story on 7-Keto (7-oxo) in the May 2005 issue: http://www.lef.org/magazine/mag2005/may2005_cover_keto_01.htm http://www.lef.org/magazine/mag2005/may2005_cover_keto_01.ht... Scientists have documented DHEA’s wide-ranging benefits in numerous clinical studies. DHEA helps to retard the effects of aging and promotes enhanced longevity, exerting a multitude of effects through its conversion to some 150 metabolites, each with unique actions within the body. One of the most important of these is 7-Keto DHEA (commonly referred to as 7-Keto), a hormone metabolite that can safely boost immune function and help reduce body fat. Unlike DHEA, however, 7-Keto does not convert to estrogen and testosterone. Because DHEA and 7-Keto have separate and unique functions and properties, it is important to understand the differences between these two popular dietary supplements. [...] A study with mice suggests that 7-Keto can boost memory as well.17 In this experiment, researchers at the University of Wisconsin in Madison trained young mice in the use of a water maze. They found that a single injection of 7-Keto (at 24 mg/kg of body weight) reversed experimentally induced memory loss. The scientists then fed 7-Keto or DHEA to old mice that had learned the maze. They discovered that memory of the water-maze training was retained during a four-week test period in the mice receiving 7-Keto but not in those treated with DHEA. The article includes 18 references.

gravitycop 18y ago

What are the downsides to this stuff? Here is one of the latest studies I could find (2007 Sep;18): http://www.ncbi.nlm.nih.gov/pubmed/17418559 http://www.ncbi.nlm.nih.gov/pubmed/17418559 This study tested the hypothesis that 3-acetyl-7-oxo-dehydroepiandrosterone alone (7-Keto) and in combination with calcium citrate, green tea extract, ascorbic acid, chromium nicotinate and cholecalciferol (HUM5007) will increase the resting metabolic rate (RMR) of overweight subjects maintained on a calorie-restricted diet. [...] In this study, the administration of HUM5007 or 7-Keto reversed the decrease in RMR normally associated with dieting. HUM5007 and 7-Keto increased RMR above basal levels and may benefit obese individuals with impaired energy expenditure. HUM5007 and 7-Keto were generally well tolerated and no serious adverse events were reported. Note that it says, "7-Keto [was] generally well tolerated and no serious adverse events were reported". Cholecalciferol is also known as Vitamin D3 and is widely available as a dietary supplement.