Fwiw, 3 mice is imho sufficient because these mice might as well be clones. They're not clones, but they're genetically very similar to one another, so variatio

Fwiw, 3 mice is imho sufficient because these mice might as well be clones. They're not clones, but they're genetically very similar to one another, so variations in results are not expected. Granted, the other concerns hold.