3 ms·
Cells don't survive sequencing, any that you do implant have not been sequenced. At best you can get some confidence that the error rate is small.
by roywiggins 10mo ago
Cells don't survive sequencing, any that you do implant have not been sequenced. At best you can get some confidence that the error rate is small.
- colechristensen 10mo agoThis is why I said build a cell _line_, i.e. cells that all come from a single parent cell. Clones. Make monoclonal stem cell lines, use CRISPR on them, make a NEW monoclonal cell line post-CRISPR and pull some cells to validate success or failure.