2 ms·

> PFHO Here we go again with the PFAS. It is the stuff to prefer the least, not the most. > I'm getting D3 and A from multivitamins That fails completely bec

> PFHO Here we go again with the PFAS. It is the stuff to prefer the least, not the most. > I'm getting D3 and A from multivitamins That fails completely because they almost always don't have softgel oil-dissolve forms or the right dose at all. They're generally very far from it. It is exactly what leads to the autoimmune issue of dry eyes in the first place.

cyberax 11mo ago
Yeah, yeah. Sure. > That fails completely because they almost always don't have softgel oil-dissolve forms or the right dose at all I tried tons of forms. My current ones are gel-filled capsules. Rather large ones, at that. Sorry, but there's a huge amount of scholarly literature on this question. I've read tons of it over the years, and there is NO magical supplement that does anything but mildly improve the situation.
- OutOfHere 11mo ago
  Forms alone won't accomplish anything if the dose isn't correct. With regard to vitamin A, some people confuse it with beta carotene, with the latter not working so well for this effect. Vitamin A even has evidence backing it as per PMC6462169. It does take a few weeks to begin to work. Even mild improvements stack up. It may not eliminate the need for an additional intervention, but it can mean the difference between whether the additional intervention will work or fail.
  - cyberax 11mo ago
    Again, I read that and tried various forms. Yes, they do help a bit. No, they don't help a lot. The study you cited find only a weak effect on some endpoints. Same for fish oil and various omega-3 acids. The effects are either weak or in some cases non-existent ( https://www.nejm.org/doi/full/10.1056/NEJMoa1709691 https://www.nejm.org/doi/full/10.1056/NEJMoa1709691 ).
    - OutOfHere 11mo ago
      It is together that things work better. It is silly to look only at an individual effect.

2 ms·

> PFHO Here we go again with the PFAS. It is the stuff to prefer the least, not the most. > I'm getting D3 and A from multivitamins That fails completely bec

by OutOfHere 11mo ago

cyberax 11mo ago
Yeah, yeah. Sure. > That fails completely because they almost always don't have softgel oil-dissolve forms or the right dose at all I tried tons of forms. My current ones are gel-filled capsules. Rather large ones, at that. Sorry, but there's a huge amount of scholarly literature on this question. I've read tons of it over the years, and there is NO magical supplement that does anything but mildly improve the situation.
- OutOfHere 11mo ago
  Forms alone won't accomplish anything if the dose isn't correct. With regard to vitamin A, some people confuse it with beta carotene, with the latter not working so well for this effect. Vitamin A even has evidence backing it as per PMC6462169. It does take a few weeks to begin to work. Even mild improvements stack up. It may not eliminate the need for an additional intervention, but it can mean the difference between whether the additional intervention will work or fail.
  - cyberax 11mo ago
    Again, I read that and tried various forms. Yes, they do help a bit. No, they don't help a lot. The study you cited find only a weak effect on some endpoints. Same for fish oil and various omega-3 acids. The effects are either weak or in some cases non-existent ( https://www.nejm.org/doi/full/10.1056/NEJMoa1709691 https://www.nejm.org/doi/full/10.1056/NEJMoa1709691 ).
    - OutOfHere 11mo ago
      It is together that things work better. It is silly to look only at an individual effect.