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Article specifically refers to vaccination with live attenuated virus... Should a difference be inferred between Shingrix and Zostavax (in the context of the ef
by ln809 10mo ago
Article specifically refers to vaccination with live attenuated virus... Should a difference be inferred between Shingrix and Zostavax (in the context of the effect on dementia, not shingles)
Background to the question is providers here seem to be switching to Shingrix for (claimed) higher effectiveness against shingles, but there's at least some suggestion that Shingix is not live (attenuated) virus...
- kieranmaine 10mo agoFrom https://www.ox.ac.uk/news/2025-06-25-how-do-vaccines-reduce-risk-dementia https://www.ox.ac.uk/news/2025-06-25-how-do-vaccines-reduce-... > The shingles vaccine now in widespread use (Shingrix) has more of an effect than the previous one (Zostavax). A key difference between these vaccines is that Shingrix contains an ‘adjuvant’, an ingredient designed to enhance the vaccine’s effect. It is therefore possible that the adjuvant contributes to Shingrix’ greater effect than Zostavax on reducing dementia.