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People have to understand that individual cases of effectively curing HIV via stem cell transplants are merely providing a few puzzle pieces to HIV research, if
by Traubenfuchs 11mo ago
People have to understand that individual cases of effectively curing HIV via stem cell transplants are merely providing a few puzzle pieces to HIV research, if at all, but have no clinical applicability, as a stem cell transplant is always an extreme, dangerous and last-resort treatment for otherwise unmanageable diseases, as which HIV generally does not count anymore.
- francisofascii 11mo agoThis is the 7th case, so this seems like a bigger puzzle piece.
- inglor_cz 11mo agoPeople also have to understand that some weapons are useful having just in case, and that we might be a few mutations away from HIV becoming unmanageable again.
- hiddencost 11mo agoI don't think you understood the parent post. The point is that this is not repeatable: curing HIV isn't something we now know how to do. The second point is: this did not give us a significant new insight into the causes or mechanisms of treatment of HIV
- Traubenfuchs 11mo ago> curing HIV isn't something we now know how to do. Technically we do but we will never ever give someone a stem cell transplant to cure their HIV because there are SIX highly effective different classes of medication to treat HIV. Majorly treatment resistant high fitness HIV is NOT a concern on the horizon. > The second point is: this did not give us a significant new insight into the causes or mechanisms of treatment of HIV The first unique cases of both variants of this DID lead to significant, valuable insights in several areas. But further cases, not so much. Myeloablation clearing the HIV reservoirs while the patient continues being on ART leading to a total cure does not excite any knowledgeable scientist anymore in 2025.