4 ms·

A Nicotine Analogue I Had Known and Didn't Love: 6-Methylnicotine

27 points by eatitraw 11mo ago

DaveZale 11mo ago
Have you tried galantamine? It's abig hit for the "lucid dreaming" crowd. Sometimes also sold formulated with theanine (brand name lucidamine) and OTC
- eatitraw 11mo ago
  I heard about it but I haven't tried. What's your experience with it like?
  - DaveZale 11mo ago
    Galantamine has similar effects to nictonine without the nervousness, and lasts hours longer. It is nootropic, cognition enhancing with few side effects. It's a natural product, so here in the US, it falls into the dietary supplement category. Sharpened memory and attention span, and enhanced dreaming for many.
- denisstp 11mo ago
  Not OP but I have extensive experience with it. I used it often in college (10+ years ago), both with and without theanine and other similar substances in my stack. The effects were noticeable and much less jittery than from nicotine. Positive: My working memory felt faster and less error-prone. I've always been good at mental math. Speed is my strength but I make lots of mistakes and things sometimes seem to "pop" out of my WM against my will. This seemed to (qualitatively) happen less often. I remember that I had some quantitative metrics on two-digit by two-digit multiplication that showed positive results, but the data is long lost to time. Negative: Mild to strong nausea and light-headedness. It often felt like I had vaped too much. This was never bad enough to negate the positive effects. Overall I think it's a useful performance enhancer for time-sensitive intellectual work, but I'm afraid it may be too strong for daily use. You will see rapid desensitization if using more than sporadically.
echelon_musk 11mo ago
Without reading the TFA the title seems like a nice reference to TiHKAL and PiHKAL.
- miningape 11mo ago
  The author's name is Sasha Putilin - might be the author's real name, but it's a lucky coincidence in that case
  - echelon_musk 11mo ago
    Later in the article he embeds a tweet that references Shulgin so the title at least is definitely intentional.
caliweed 11mo ago
Substack uses the email as the placeholder, it prefills the subscribe input. And it can't even be erased with backspace. Basically if you're streaming or having any kind of observation they're gonna see your email.
proxysna 11mo ago
Subscription form looks like a cigarette with a white field for an email and orange submit button. Nice touch/conicidence.
joemazerino 11mo ago
Glad I'm reading this while on a nicotine break...

27 points by eatitraw 11mo ago

Have you tried galantamine? It's abig hit for the "lucid dreaming" crowd. Sometimes also sold formulated with theanine (brand name lucidamine) and OTC

eatitraw 11mo ago
I heard about it but I haven't tried. What's your experience with it like?
- DaveZale 11mo ago
  Galantamine has similar effects to nictonine without the nervousness, and lasts hours longer. It is nootropic, cognition enhancing with few side effects. It's a natural product, so here in the US, it falls into the dietary supplement category. Sharpened memory and attention span, and enhanced dreaming for many.
denisstp 11mo ago
Not OP but I have extensive experience with it. I used it often in college (10+ years ago), both with and without theanine and other similar substances in my stack. The effects were noticeable and much less jittery than from nicotine. Positive: My working memory felt faster and less error-prone. I've always been good at mental math. Speed is my strength but I make lots of mistakes and things sometimes seem to "pop" out of my WM against my will. This seemed to (qualitatively) happen less often. I remember that I had some quantitative metrics on two-digit by two-digit multiplication that showed positive results, but the data is long lost to time. Negative: Mild to strong nausea and light-headedness. It often felt like I had vaped too much. This was never bad enough to negate the positive effects. Overall I think it's a useful performance enhancer for time-sensitive intellectual work, but I'm afraid it may be too strong for daily use. You will see rapid desensitization if using more than sporadically.

echelon_musk 11mo ago

Without reading the TFA the title seems like a nice reference to TiHKAL and PiHKAL.

miningape 11mo ago
The author's name is Sasha Putilin - might be the author's real name, but it's a lucky coincidence in that case
- echelon_musk 11mo ago
  Later in the article he embeds a tweet that references Shulgin so the title at least is definitely intentional.

caliweed 11mo ago

Substack uses the email as the placeholder, it prefills the subscribe input. And it can't even be erased with backspace. Basically if you're streaming or having any kind of observation they're gonna see your email.

proxysna 11mo ago

Subscription form looks like a cigarette with a white field for an email and orange submit button. Nice touch/conicidence.

joemazerino 11mo ago

Glad I'm reading this while on a nicotine break...