Ah indeed I read more in your comment than you actually wrote. Regarding free samples, it's a good point that I overlooked. According to reference [3] above, f

Ah indeed I read more in your comment than you actually wrote. Regarding free samples, it's a good point that I overlooked. According to reference [3] above, free samples account for 28% of marketing expenditures. The remaining 72% still represent 18% of revenues spent on pure marketing. So even if all free samples were used by doctors to help the poorer patients, there is arguably more money spent on marketing than R&D.