If you know that you don't have customers or users in the area, or very few, then go for it. I worked in e-commerce previously, we reduce fraud to almost zero

If you know that you don't have customers or users in the area, or very few, then go for it. I worked in e-commerce previously, we reduce fraud to almost zero by banning non-local cards. It affected a few customers that had international credit cards, but not enough to justify dealing with the fraud. Sometimes you just need to limit your attack surface.