3 ms·

Is there evidence for addiction tendencies in general? Or is it something specific to alcohol?

surfsvammel 11mo ago
I don’t know! Think I’ve seen a headline somewhere, but can’t remember where. Quick search should help you :) To me, it’s anecdotal, of course, but I have same sense of being in control over alcohol intake as food intake. Basically makes it much easier for me to avoid binging.
zemvpferreira 11mo ago
I’m about to go to the cinema so I can’t find you references, but there’s a lot of anecdotal evidence at least of glp1’s curbing all sorts of addictive behaviour. I personally started Mounjaro last week and my coffee cravings have gone way, way down for the first time in my adult life.
SoftTalker 11mo ago
I believe there is, I don't recall the source but have read that these drugs work by reducing cravings. So they have shown at least hints that they can work on any addictive behavior, not just overeating.
toomuchtodo 11mo ago
A Brain Reward Circuit Inhibited By Next-Generation Weight Loss Drugs - https://www.biorxiv.org/content/10.1101/2024.12.12.628169v1.full https://www.biorxiv.org/content/10.1101/2024.12.12.628169v1.... | https://doi.org/10.1101/2024.12.12.628169 https://doi.org/10.1101/2024.12.12.628169 - December 17rd, 2024 Glucagon-like peptide 1 agonist and effects on reward behaviour: A systematic review - https://www.sciencedirect.com/science/article/pii/S0031938424001677 https://www.sciencedirect.com/science/article/pii/S003193842... | https://doi.org/10.1016/j.physbeh.2024.114622 https://doi.org/10.1016/j.physbeh.2024.114622 - Physiology & Behavior Volume 283, 1 September 2024, 114622 GLP-1 for Addiction: the Medical Evidence for Opioid, Nicotine, and Alcohol Use Disorder - https://recursiveadaptation.com/p/the-growing-scientific-case-for-using https://recursiveadaptation.com/p/the-growing-scientific-cas... - May 14th, 2024 The central GLP-1: implications for food and drug reward - https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2013.00181/full https://www.frontiersin.org/journals/neuroscience/articles/1... | https://doi.org/10.3389/fnins.2013.00181 https://doi.org/10.3389/fnins.2013.00181 - Front. Neurosci., October 13th, 2013
CobrastanJorji 11mo ago
From my friends on GLP-1s, I'm pretty sure that it's mostly that it makes you really sick fairly quickly when you drink even in moderation.

I don’t know! Think I’ve seen a headline somewhere, but can’t remember where. Quick search should help you :) To me, it’s anecdotal, of course, but I have same sense of being in control over alcohol intake as food intake. Basically makes it much easier for me to avoid binging.

zemvpferreira 11mo ago

I’m about to go to the cinema so I can’t find you references, but there’s a lot of anecdotal evidence at least of glp1’s curbing all sorts of addictive behaviour. I personally started Mounjaro last week and my coffee cravings have gone way, way down for the first time in my adult life.

SoftTalker 11mo ago

I believe there is, I don't recall the source but have read that these drugs work by reducing cravings. So they have shown at least hints that they can work on any addictive behavior, not just overeating.

toomuchtodo 11mo ago

A Brain Reward Circuit Inhibited By Next-Generation Weight Loss Drugs - https://www.biorxiv.org/content/10.1101/2024.12.12.628169v1.full https://www.biorxiv.org/content/10.1101/2024.12.12.628169v1.... | https://doi.org/10.1101/2024.12.12.628169 https://doi.org/10.1101/2024.12.12.628169 - December 17rd, 2024 Glucagon-like peptide 1 agonist and effects on reward behaviour: A systematic review - https://www.sciencedirect.com/science/article/pii/S0031938424001677 https://www.sciencedirect.com/science/article/pii/S003193842... | https://doi.org/10.1016/j.physbeh.2024.114622 https://doi.org/10.1016/j.physbeh.2024.114622 - Physiology & Behavior Volume 283, 1 September 2024, 114622 GLP-1 for Addiction: the Medical Evidence for Opioid, Nicotine, and Alcohol Use Disorder - https://recursiveadaptation.com/p/the-growing-scientific-case-for-using https://recursiveadaptation.com/p/the-growing-scientific-cas... - May 14th, 2024 The central GLP-1: implications for food and drug reward - https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2013.00181/full https://www.frontiersin.org/journals/neuroscience/articles/1... | https://doi.org/10.3389/fnins.2013.00181 https://doi.org/10.3389/fnins.2013.00181 - Front. Neurosci., October 13th, 2013

CobrastanJorji 11mo ago

From my friends on GLP-1s, I'm pretty sure that it's mostly that it makes you really sick fairly quickly when you drink even in moderation.