4 ms·
But also be careful about taking too much choline. There's lots of anecdotal reports of people taking too much choline supplements and becoming massively depres
by Trasmatta 11mo ago
But also be careful about taking too much choline. There's lots of anecdotal reports of people taking too much choline supplements and becoming massively depressed.
- zamalek 11mo agoInterestingly many antidepressants are anticholinergic (as are many nootropes, so you have to be super careful mixing to the two).
- deleted 11mo ago[deleted]
- clumsysmurf 11mo agoThe other problem with supplementing with too much choline may be elevated TMAO: "Dietary Choline Supplements, but Not Eggs, Raise Fasting TMAO Levels in Participants with Normal Renal Function: A Randomized Clinical Trial" https://pmc.ncbi.nlm.nih.gov/articles/PMC8410632/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8410632/
- brigandish 11mo agoIt helps to mention what TMAO is: > Choline is a dietary precursor to the gut microbial generation of the pro-thrombotic and pro-atherogenic metabolite trimethylamine-N-oxide (TMAO).
- JKCalhoun 11mo agoHelped a little?
- JKCalhoun 11mo agoMy takeaway: do please go ahead and add egg to your diet.
- tucnak 11mo agoBig Egg paid you to say this, didn't they?
- DANmode 11mo agoI do prefer a Big Egg. Brown ones, too. I haven’t looked, but I bet that tracks with nutritional value.
- ndsipa_pomu 11mo agoThere's no nutritional difference between brown and white eggs
- tucnak 11mo agoExactly something that the white egg-faction of Big Egg cartel would pay you to say.
- ndsipa_pomu 11mo agoDagnammit - they're onto us and our misinformation campaign. Best get back to just painting them brown.
- DANmode 11mo agoBut brown does usually mean "biggest egg you're going to get here"!
- ndsipa_pomu 11mo agoYep brown eggs are laid by brown/red coloured breeds which do tend to be larger than white hens. They have the same nutritional profile though.
- deleted 11mo ago[deleted]
- majso 11mo agoIt seems that the active form of choline, phosphatidylcholine, also did not increase TMAO levels.