4 ms·

Endorphins? Where's the link to the science? http://www.runnersworld.com/article/0,7120,s6-243-297--1102-0,00.html http://www.runnersworld.com/article/0,7120,s

Endorphins? Where's the link to the science? http://www.runnersworld.com/article/0,7120,s6-243-297--1102-0,00.html http://www.runnersworld.com/article/0,7120,s6-243-297--1102-... quote: "I believe this endorphin in runners is a total fantasy in the pop culture," said psychobiologist Huda Akil, Ph.D., from the University of Michigan. The endorphin theory had several problems, the most serious being that endorphins are too large to pass through the blood-brain barrier that border-patrols your gray matter.

gbaygon 14y ago
A sentense that begins with "I believe..." may not be the best example of science, a better way to express himself could have been "[X] study has demonstrated...".
Void_ 14y ago
It's one of those "life hacks" articles, I wouldn't expect too much science behind it.
taroth 14y ago
Interesting. Huda Akil is no obscure quack. http://scholar.google.com/scholar?hl=en&q=Huda+Akil&btnG=&as_sdt=1%2C5&as_sdtp= http://scholar.google.com/scholar?hl=en&q=Huda+Akil&...
- bduerst 14y ago
  Could be more than one person with that name.
3am_hackernews 14y ago
As with most of the neuroscience research, there exists a counter evidence to this - Boecker, H., Sprenger, T., Spilker, M.E., Henriksen, G., Koppenhoefer, M., Wagner, K.J., Valet, M., Berthele, A., Tolle, T.R. (2008). The Runner's High: Opioidergic Mechanisms in the Human Brain. Cerebral Cortex DOI: 10.1093/cercor/bhn013[http://cercor.oxfordjournals.org/content/18/11/2523.full http://cercor.oxfordjournals.org/content/18/11/2523.full]
- zerostar07 14y ago
  Other study shows that the effect is mediated through endocannabinoids not endorphins (But the effect is very real): http://www.ncbi.nlm.nih.gov/pubmed/14625449 http://www.ncbi.nlm.nih.gov/pubmed/14625449
recursive 14y ago
There's a lot of personal (anecdotal) accounts that it's real. I don't care if it's placebo or something more sciencey. It works for many people, and it works for me.
- nollidge 14y ago
  OP never said it's not real, just that endorphins are not conclusively the cause.
desireco42 14y ago
See I never questioned this, yet this makes total sense now. Thanks for posting this, I am surprised I didn't know about this before. Kind of, opens my eyes.

gbaygon 14y ago

A sentense that begins with "I believe..." may not be the best example of science, a better way to express himself could have been "[X] study has demonstrated...".

Void_ 14y ago

It's one of those "life hacks" articles, I wouldn't expect too much science behind it.

taroth 14y ago

Interesting. Huda Akil is no obscure quack. http://scholar.google.com/scholar?hl=en&q=Huda+Akil&btnG=&as_sdt=1%2C5&as_sdtp= http://scholar.google.com/scholar?hl=en&q=Huda+Akil&...

bduerst 14y ago
Could be more than one person with that name.

3am_hackernews 14y ago

As with most of the neuroscience research, there exists a counter evidence to this - Boecker, H., Sprenger, T., Spilker, M.E., Henriksen, G., Koppenhoefer, M., Wagner, K.J., Valet, M., Berthele, A., Tolle, T.R. (2008). The Runner's High: Opioidergic Mechanisms in the Human Brain. Cerebral Cortex DOI: 10.1093/cercor/bhn013[http://cercor.oxfordjournals.org/content/18/11/2523.full http://cercor.oxfordjournals.org/content/18/11/2523.full]

zerostar07 14y ago
Other study shows that the effect is mediated through endocannabinoids not endorphins (But the effect is very real): http://www.ncbi.nlm.nih.gov/pubmed/14625449 http://www.ncbi.nlm.nih.gov/pubmed/14625449

recursive 14y ago

There's a lot of personal (anecdotal) accounts that it's real. I don't care if it's placebo or something more sciencey. It works for many people, and it works for me.

nollidge 14y ago
OP never said it's not real, just that endorphins are not conclusively the cause.

desireco42 14y ago

See I never questioned this, yet this makes total sense now. Thanks for posting this, I am surprised I didn't know about this before. Kind of, opens my eyes.