I have the same feeling, so I just looked it up and actually uv does support exactly that mode. It works the same as venv and pip but you just prefix a bunch of

I have the same feeling, so I just looked it up and actually uv does support exactly that mode. It works the same as venv and pip but you just prefix a bunch of commands with "uv". Create a new virtual environment fooenv: uv venv fooenv Activate virtual environment on Windows (yes I'm sorry that's what I'm currently typing on!): .\fooenv\Scripts\activate Run some environment commands: uv pip install numpy uv pip freeze uv pip uninstall numpy If you run python now, it will be in this virtual environment. You can deactivate it with: deactivate Admittedly, there doesn't seem to be much benefit compared to traditional venv/pip for this use case. This is covered in the section of the docs titled "The pip interface": https://docs.astral.sh/uv/pip/ https://docs.astral.sh/uv/pip/