Some people tolerate ibuprofen just fine. Some people tolerate it fine for decades, and then one day they don't. It is easy to tell if ibuprofen is the cause o

Some people tolerate ibuprofen just fine. Some people tolerate it fine for decades, and then one day they don't. It is easy to tell if ibuprofen is the cause of an ulcer or not. If it is, the ulcer pain will likely start after say 72 hours of taking ibuprofen. If a week goes by without such pain, then it's not a cause in that dose. In those vulnerable, a single dose can be enough to cause it if strong preventative measures aren't taken. If your friend persistently has an unhealed ulcer, then it's worthwhile to get it healed asap before experimenting with ibuprofen. I have had it a few times, also healed it every time.