> We are (still) firmly in the sequencing by synthesis era. It really depends what your goals are. At the NAO we use Illumina with their biggest flow cell (25B

> We are (still) firmly in the sequencing by synthesis era. It really depends what your goals are. At the NAO we use Illumina with their biggest flow cell (25B) for wastewater because the things we're looking for (ex: respiratory viruses) are a small fraction of the total nucleic acids and we need the lowest cost per base pair. But when we sequence nasal swabs these viruses are a much higher fraction, and the longer reads and lower cost per run of Nanopore make it a better fit.