I completely agree that the risk/benefit risk of these drugs isn't good. But to me, the fact that these anti amyloid drugs show even modest effect on cognition

I completely agree that the risk/benefit risk of these drugs isn't good. But to me, the fact that these anti amyloid drugs show even modest effect on cognition puts the burden of proof back on the amyloid skeptics, since removing amyloid changes at least somewhat the course of the disease.