4 ms·
See https://www.astralcodexten.com/p/in-defense-of-the-amyloid-hypothesis https://www.astralcodexten.com/p/in-defense-of-the-amyloid-h... for an IMO compelling
by orangecat 1y ago
See https://www.astralcodexten.com/p/in-defense-of-the-amyloid-hypothesis https://www.astralcodexten.com/p/in-defense-of-the-amyloid-h... for an IMO compelling argument that amyloid really is the underlying cause. The theory is that amyloid buildup causes misfolded tau proteins which cause the cognitive damage. So reducing amyloid in people already suffering from Alzheimer's doesn't do much because they already have excessive tau; at best it might slow down the progression.
- mcmoor 1y agoI've read this article before, and it makes me think OP article, even if working on humans, would still not alleviate Alzheimer.
- erredois 1y agoIf successfull it could slow progression, and with better detection eventually greatly reduce the impact. Of course the whole thing could not happen, but i don't think we can say it will not happen right now.