Taking finasteride means higher œstrogen levels, and reduced androgenic activity. There are subtle differences between the effect of testosterone and DHT (it's

Taking finasteride means higher œstrogen levels, and reduced androgenic activity. There are subtle differences between the effect of testosterone and DHT (it's not just that DHT is a more potent androgen), but I wouldn't expect the effects of higher testosterone to counteract the effect of significantly-reduced DHT. Of course, the effects aren't too significant for most adult cis men, other than reduced hair loss. I'm bringing up trans HRT in the 1930s (got the decade wrong, sorry!) because the Nobel Prize for the synthesis of testosterone was awarded in 1939. That discovery was made at the start of our understanding of what happens when you muck around with sex steroids: "what effect does this have on mental health?" has always been a question that people have considered, and I was frankly shocked by the article's claim that it hadn't been properly considered in the US. Of course, others have pointed out that this article is more of a hit piece than a scientific work, so it appears my surprise was justified.