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To be clear, what the researchers & AI here have discovered is not a treatment for IBD per se. Rather, the gut of some people, especially people with IBD and p
by Centigonal 1y ago
To be clear, what the researchers & AI here have discovered is not a treatment for IBD per se.
Rather, the gut of some people, especially people with IBD and people who have received broad spectrum antibiotics, can be colonized by enterobacter species. These are bacteria (including some kinds of E. Coli) that are resistant to broad spectrum antibiotics, and this overgrowth is not good for gut health. The researchers have discovered a compound that appears to fight these enterobacter species without destroying the larger gut microbiome. This could help people (especially people with IBD) whose gut has been taken over by this kind of bacteria get back to a more normal gut microbiome, although only mouse studies have been done so far.
- standardUser 1y agoThe article continues... “This new drug is a really promising treatment candidate for the millions of patients living with IBD... We currently have no cure for these conditions, so developing something that might meaningfully alleviate symptoms could help people experience a much higher quality of life.”
- thorum 1y agoIt’s long been theorized (not proven) that fully balancing the microbiome in IBD patients might interrupt the disease cycle and lead to remission.
- FollowingTheDao 1y agoCrohn's is most certainly started by E. Coli infection... https://www.gastroenterologyadvisor.com/news/escherichia-coli-may-be-associated-with-pathogenesis-of-ibd/ https://www.gastroenterologyadvisor.com/news/escherichia-col...