3 ms·
not exactly but E. coli and other Enterobacteriaceae can actually use the inflammation to their advantage Inflammation release nitrates, which Enterobacteriace
by pazimzadeh 1y ago
not exactly but E. coli and other Enterobacteriaceae can actually use the inflammation to their advantage
Inflammation release nitrates, which Enterobacteriaceae can use as a replacement for oxygen as a terminal electron acceptor
They can also encroach more easily on the protective mucus layers, which are thinner and more porous during inflammatory conditions (which itself may be a result of a messed up microbiota, which is why broad-spectrum antibiotics are not a solution)
These Enterobacteriaceae blooms in turn can cause inflammation, makes remission harder
There has been some success in reducing inflammation levels in IBD by blocking some of the binding factors that E. coli uses to attach to the epithelium/mucus