Interesting. In the early 90s, lots of protein servers, i.e. the predecessors of AlphaFold et al., were also using email as UI. You'd submit query sequences as

Interesting. In the early 90s, lots of protein servers, i.e. the predecessors of AlphaFold et al., were also using email as UI. You'd submit query sequences as an email, and get an email back with predictions. The input format has not changed, still FASTA.