I don't think that the assertions are nonsense, but I don't understand how this works. I have heard variants on this assertion: "Two of the most prominent pur

I don't think that the assertions are nonsense, but I don't understand how this works. I have heard variants on this assertion: "Two of the most prominent purported underlying causes of aging are chronic inflammation and senescent cells." One thing that surprises me is that telomeres aren't mentioned. I also don't understand how this is happening (is apoptosis somehow triggered?): "Now, the Academy researchers demonstrate that SRCs reduce senescent cells, measured using a blue dye called SA-β-Gal, in multiple organs, including the brain, heart, and lungs." The main mechanism of action appears to be: "The therapeutic efficacy of MPCs is largely attributed to their paracrine actions, with exosomes playing a pivotal role in mediating these effects." The researchers do not appear to fully understand how this is happening: "Among the diverse geroprotective functions of SRCs in the brain and ovary, the restorative effect of SRC-derived exosomes on aged cells and their surroundings emerges as a key mechanism. Rejuvenation of aged cells by exosomes likely involves multiple pathways and targets."