So the best way to get induced pluripotent stem cells is through the Yamanaka factors, which are proteins coded for by genes which are not expressed in mature c

So the best way to get induced pluripotent stem cells is through the Yamanaka factors, which are proteins coded for by genes which are not expressed in mature cells. Using all four Yamanaka factors is a one-way ticket to tumor town. But, as it turns out, using three of the four still gets you IPSCs without the elevated cancer risk.