3 ms·

You forgot to mention that statins are an anti-inflammatory as well. This argument itself fails on that

• cthalupa 1y ago
  PCSK9 inhibitors do not universally lower hsCRP but still reduce cardiovascular events. https://pmc.ncbi.nlm.nih.gov/articles/PMC4876179/ https://pmc.ncbi.nlm.nih.gov/articles/PMC4876179/ https://pubmed.ncbi.nlm.nih.gov/36779348/ https://pubmed.ncbi.nlm.nih.gov/36779348/ MR studies on genetics show that LDL and Lp(a) are independent risk factors for cardiovascular events regardless of hsCRP https://www.nejm.org/doi/full/10.1056/NEJMoa1109034 https://www.nejm.org/doi/full/10.1056/NEJMoa1109034 https://pmc.ncbi.nlm.nih.gov/articles/PMC5483508/ https://pmc.ncbi.nlm.nih.gov/articles/PMC5483508/ https://europepmc.org/article/med/20032323 https://europepmc.org/article/med/20032323 https://journals.plos.org/plosmedicine/article%3Fid%3D10.1371/journal.pmed.1003062 https://journals.plos.org/plosmedicine/article%3Fid%3D10.137... https://www.nejm.org/doi/full/10.1056/NEJMoa1604304 https://www.nejm.org/doi/full/10.1056/NEJMoa1604304 https://pubmed.ncbi.nlm.nih.gov/23083789/ https://pubmed.ncbi.nlm.nih.gov/23083789/