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I'm a bit late to this, but if you're still around, I'm curious if this research would necessarily mean that people with sleep apnea or other sleep disorders (u

I'm a bit late to this, but if you're still around, I'm curious if this research would necessarily mean that people with sleep apnea or other sleep disorders (untreated or treated) are more prone to Alzheimer's as they age? I'm also curious if there's been any research on your technology being used on people who have sleep disorders. I took a look at the research you linked, but the second paper noted that people with sleep disorders were excluded from the study, and the first paper didn't mention sleep disorders or apneas at all. I ask as someone who has sleep apnea and uses a CPAP machine.

pedalpete 1y ago
My understanding is there is a directional correlation between untreated sleep apnea and Alzheimer's. Do you feel your CPAP improves your mental clarity, or mood? The reason I ask is the cognitive benefits of CPAP are inconclusive. It works in some people, not in others. It solves the hypopnea, but that doesn't mean slow-wave activity increases as a result. There is no research I'm aware of that has been published showing how slow-wave enhancement impacts people with sleep apnea. We work out of The University of Sydney, where CPAP was invented and work with a few former ResMed employees, and know a bunch of people who still work at ResMed. When we approached them a few years ago, they didn't seem very interested, but the science has progressed significantly since then, and it's getting pretty difficult to ignore it. I'll reach out and see if they're keen on supporting a study. BTW, have you tried a mandibular splint (biteplate)? My brother was on CPAP for about 8 years, and then moved to a moved to the biteplate about a year ago. He's MUCH happier with it.