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really cool Im sorry to hear you didnt get funding. I dont know much but isnt the problem related to what causes the build up in teh first place? wasnt it scarr
by ionwake 1y ago
really cool Im sorry to hear you didnt get funding. I dont know much but isnt the problem related to what causes the build up in teh first place? wasnt it scarring or something?
- pedalpete 1y agoThanks. We're used to not getting funding. It's part of the journey as a start-up and in research. The build-up isn't scarring. It's misfolded proteins in the brain which stick in places they shouldn't and the glymphatic system which flushes cerebrospinal fluid through the brain removes the build-up of these protiens. If you have poor sleep or lack of sleep, these proteins don't get removed and that build-up interferes and disrupts the firing of neurons. Alzheimer's drugs are able to help remove the build-up, but unfortunately are not able to repair the damage. That's why they only slow progression of the disease, not treat it. If slow-wave enhancement lives up to the potential, it would likely also only be preventative. It would be surprising if it was able to treat AD. If you want to know more, a comment in this post has what I think may be the most thorough breakdown of AD. https://www.astralcodexten.com/p/in-defense-of-the-amyloid-hypothesis https://www.astralcodexten.com/p/in-defense-of-the-amyloid-h...
- ionwake 1y agoGreat stuff thank you!