3 ms·

Thanks. A researcher we work with has postulated that build-up of metabolic waste (amyloid and tau, among others) directly impairs the glymphatic system, leadin

Thanks. A researcher we work with has postulated that build-up of metabolic waste (amyloid and tau, among others) directly impairs the glymphatic system, leading to more build-up. A viscous cycle. I don't think she's the first to postulate this, but I believe she is researching this relationship now. Though work culture is an important one, we're somewhat more focused on the less self-imposed sleep challenges related to maternity and perimenopause/menopause.

DaveZale 1y ago
that's a cute Freudian slip (or deliberate joke) - viscous cycle - sure, amyloid and tau are probably very viscous when you poke at them with the laboratory utensil of your choice. And accumulation of them is like a viscious cycle of plaque accumulation and even worse clearance. It seems exponetial
- maybelsyrup 1y ago
  Came here to say this. Also lol: > And accumulation of them is like a viscious cycle I don’t know what this slip meant though ;-)
- pedalpete 1y ago
  LOL :) Unintentional, but I like it!