There are downsides and side-effects to metformin. I started taking it for life-extension and maybe weight loss support, not for diabetes. A few months in I st

There are downsides and side-effects to metformin. I started taking it for life-extension and maybe weight loss support, not for diabetes. A few months in I started getting pain from my buttocks to my calves whenever I sit for more than 15 minutes. I was concerned that this was some new misery life had thrown at me, but when I looked up the symptoms I found that this is an uncommon side effect of metformin for some people. This sensation greatly decreased after ceasing metformin, but has not completely subsided 2 months later. I'm fortunate to have a standing desk at work, but the only way to temporarily mitigate this issue is to go for a long walk or otherwise exercise. I'm not against it. It helps many people with lots of things, just putting this information out for people who might experience the same issue. Hopefully with this new understanding they will come up with alternatives with lesser issues or that work for people with my response to the medicine.