4 ms·
Polylaminin, a drug considered capable of reversing spinal cord injury
- animitronix 1y ago[flagged]
- Enginerrrd 1y agoHey FYI, this isnt the place for that type of comment. This isn't Reddit, and we don't want it to become such. Unnuanced, potentially inflammatory quips about a vaguely related current political situation just aren't appropriate here. There are plenty of ways to express the same sentiment without resorting to the type of commentary that is common elsewhere. I encourage you to read the community guidelines for HN.
- s5300 1y ago[dead]
- voxleone 1y agoPaper: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109388 https://journals.plos.org/plosone/article?id=10.1371/journal...
- mmaia 1y agoPublished: October 8, 2014 More recent work indexed in Google Scholar: https://scholar.google.com/citations?hl=en&user=TVozLNoAAAAJ&view_op=list_works&sortby=pubdate https://scholar.google.com/citations?hl=en&user=TVozLNoAAAAJ...
- giarc 1y agoThat paper is an in vitro demonstration whereas the OP article seems to imply they tested on actual patients?
- lucasqueiroz 1y agoYes, it was tested on patients. @ bfdrummond on Instagram was the first one - he is now almost 100% recovered
- heavyset_go 1y agoDo we know of other patients? Sometimes drug and medical device companies will gag patients with non-disparagement agreements, while letting the success stories post freely on social media to promote their product/procedure/etc.
- zipy124 1y agoI think it's actually this one, or perhaps a new one after it: https://www.medrxiv.org/content/10.1101/2024.02.19.24301010v1.full https://www.medrxiv.org/content/10.1101/2024.02.19.24301010v...
- klipklop 1y agoI find this part most interesting: "Three participants (2, 7, 8) regained motor control. i.e., converted to AIS C or D, at the 1-month examination. Other three (4, 5, 6) converted to grade C after 3 months. In the present study we observed that, in contrast to the expected baseline conversion of 15%, 75% (6/8) of the participants regained voluntary motor control after polylaminin treatment. If we consider only those participants that reached discharge, the proportion increases to 100% (6/6)."
- deleted 1y ago[deleted]
- lucasqueiroz 1y agoMore details: https://ensaiosclinicos.gov.br/news/331 https://ensaiosclinicos.gov.br/news/331
- OptionOfT 1y agoThis is fantastic news. A good friend of mine spent years doing research at Caltech in basically trying to bridge the severed part of the spinal column with electrodes. In mice that is. The department got lots of $ from the Christopher & Dana Reeve Foundation to help them in said research.