One approach is directed energy, there are laser guns like the UK's dragonfire (there are many others out there too) however these have problems in dusty or fog

One approach is directed energy, there are laser guns like the UK's dragonfire (there are many others out there too) however these have problems in dusty or foggy conditions for obvious reasons. There are also microwave effectors which are used to fry the electronics on drones. These take advantage of the advances in Gallium Nitride based power electronics (and other even more exotic materials).