As somebody who's written and maintained a good bit of Python in prod and recently a good amount of server-side typescript... this would be my answer. I'd add

As somebody who's written and maintained a good bit of Python in prod and recently a good amount of server-side typescript... this would be my answer. I'd add one other aspect that we sort of take for granted these days, but affordable multi-threaded CPUs have really taken off in the last 10 years. Not only does the stack based on green-threads "just work" without coloring your codebase with async/no-async, it allows you to scale a single compute instance gracefully to 1 instance with N vCPUs vs N pods of 2-vCPU instances.