5 ms·
I can't read the full article (paywalls...grumble...), but this[1] would indicate better-than-placebo performance for those with major depression. Please don't
by SoftwareMaven 14y ago
I can't read the full article (paywalls...grumble...), but this[1] would indicate better-than-placebo performance for those with major depression.
Please don't spread unsubstantiated rumors on this topic. As many of us know from personal experience, the results of giving people an excuse to say "that medicine doesn't work anyway" can be devastating.
1. http://psycnet.apa.org/psycinfo/1991-19312-001 http://psycnet.apa.org/psycinfo/1991-19312-001
- philwelch 14y agoI've gathered that selective publication of results is the main problem, actually.
- SoftwareMaven 14y agoIndeed[1]. It seems to be endemic of the entire medical field[2][3] and even further removed[4]. Combined with how difficult (if not impossible) it is to reproduce many findings[5], I would call these the most important problems in science today. Science cannot move forward without all of the data (positive and negative) in a reproducible fashion. 1. http://www.ncbi.nlm.nih.gov/pubmed/18199864 http://www.ncbi.nlm.nih.gov/pubmed/18199864 2. http://journals.lww.com/greenjournal/Citation/2003/09000/Evidence_b_i_ased_medicine_selective_reporting.40.aspx http://journals.lww.com/greenjournal/Citation/2003/09000/Evi... 3. http://jama.jamanetwork.com/article.aspx?articleid=198809 http://jama.jamanetwork.com/article.aspx?articleid=198809 4. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0018362 http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjourna... 5. http://online.wsj.com/article/SB10001424052970203764804577059841672541590.html http://online.wsj.com/article/SB1000142405297020376480457705...
- Alex3917 14y ago"Please don't spread unsubstantiated rumors on this topic." You're the one spreading misinformation. How about you actually read some books on the topic before attacking others.