Not quite to the level of explain, but what one only needs is an excellent liver. This is mostly a matter of yet unknown genetics. We know a few variants where

Not quite to the level of explain, but what one only needs is an excellent liver. This is mostly a matter of yet unknown genetics. We know a few variants where different variants of classes of lipids are made reducing the risk for cardiovascular disease... If you have a bad one like myself, you go decent diet and still have metabolic syndrome by 20. (No diabetes at least. Yet.)