3 ms·

Even if we can't do it biologically i wonder how much we could extend it with artificial organs? Most deaths seem to be cardiovascular, heart disease, stroke,

Even if we can't do it biologically i wonder how much we could extend it with artificial organs? Most deaths seem to be cardiovascular, heart disease, stroke, then followed by cancer.

raluk 1y ago
Given that you die, when one vital organ dies it will eventaully hapen in this way or another. I read somwhere and that stuck in my brain, that maxmimal logevity for humans is estimated to be approximetly 125 years.
- Windchaser 1y ago
  >> I read somwhere and that stuck in my brain, that maxmimal logevity for humans is estimated to be approximetly 125 years. Oh, that's just derived from old theology. Genesis 6:3, 'Then the LORD said, “My Spirit will not contend with humans forever, for they are mortal; their days will be a hundred and twenty years.”' This kinda got spread throughout the zeitgeist long ago as a "maximal lifespan", but the reality is that only 3 in 10,000 even make it to 100. There's no hard cutoff, but functionally essentially no one gets to 110. Scientifically, there's no hard reason we couldn't increase our lifespans indefinitely, but we've got a lot of work to do before we'll be able to get a reasonable number of people up to 125.
  - binary132 1y ago
    That doesn’t sound like you’re disagreeing with gp.
sockaddr 1y ago
If we count a permanently inflamed organic blob in roughly the shape of a mouse covered by surgical scars constantly pumped with anti-rejection drugs and hooked up to a blood filter we could probably make the mouse immortal now. It might not enjoy living though.
- BriggyDwiggs42 1y ago
  I mean, that’s a good start honestly. Makes me optimistic about the QoL the mouse might be able to have in 50 years.
- kulahan 1y ago
  Funnily enough, chronic inflammation (inflammaging) is also a hallmark of aging.
kulahan 1y ago
Probably quite a bit, but some of the hallmarks (decreased intercellular signaling, reduced ATP activity, decreased macroautophagy) seem so systemic I’m not sure we’re even close.

Even if we can't do it biologically i wonder how much we could extend it with artificial organs? Most deaths seem to be cardiovascular, heart disease, stroke, then followed by cancer.

raluk 1y ago

Given that you die, when one vital organ dies it will eventaully hapen in this way or another. I read somwhere and that stuck in my brain, that maxmimal logevity for humans is estimated to be approximetly 125 years.

Windchaser 1y ago
>> I read somwhere and that stuck in my brain, that maxmimal logevity for humans is estimated to be approximetly 125 years. Oh, that's just derived from old theology. Genesis 6:3, 'Then the LORD said, “My Spirit will not contend with humans forever, for they are mortal; their days will be a hundred and twenty years.”' This kinda got spread throughout the zeitgeist long ago as a "maximal lifespan", but the reality is that only 3 in 10,000 even make it to 100. There's no hard cutoff, but functionally essentially no one gets to 110. Scientifically, there's no hard reason we couldn't increase our lifespans indefinitely, but we've got a lot of work to do before we'll be able to get a reasonable number of people up to 125.
- binary132 1y ago
  That doesn’t sound like you’re disagreeing with gp.

sockaddr 1y ago

If we count a permanently inflamed organic blob in roughly the shape of a mouse covered by surgical scars constantly pumped with anti-rejection drugs and hooked up to a blood filter we could probably make the mouse immortal now. It might not enjoy living though.

BriggyDwiggs42 1y ago
I mean, that’s a good start honestly. Makes me optimistic about the QoL the mouse might be able to have in 50 years.
kulahan 1y ago
Funnily enough, chronic inflammation (inflammaging) is also a hallmark of aging.

kulahan 1y ago

Probably quite a bit, but some of the hallmarks (decreased intercellular signaling, reduced ATP activity, decreased macroautophagy) seem so systemic I’m not sure we’re even close.