Nope, RequireJS can load any kind of Javascript dependency, even if it doesn't use the AMD format. You can even specify dependencies for non-AMD scripts in the

Nope, RequireJS can load any kind of Javascript dependency, even if it doesn't use the AMD format. You can even specify dependencies for non-AMD scripts in the configuration object.[0] As for define(), there's only one AMD method signature: define([[name,] deps,] fn). Any loader that does not accept this signature cannot legitimately call itself an AMD loader. [0] http://requirejs.org/docs/api.html#config-shim http://requirejs.org/docs/api.html#config-shim