3 ms·

and sometimes banana is simply banana: Hypercatabolic syndrome (HS) is a biochemical state characterized by increased circulating catabolic hormones (eg, corti

by tguvot 1y ago

and sometimes banana is simply banana: Hypercatabolic syndrome (HS) is a biochemical state characterized by increased circulating catabolic hormones (eg, cortisol, catecholamines) and inflammatory cytokines (eg, tumor necrosis factors, interleukin–1β), and decreased anabolic insulin effects with consequent insulin resistance. The most important metabolic consequence of HS is the skeletal and cardiac muscle protein breakdown that releases amino acids (AAs), which in turn supports indispensable body energy requirements but also reduces skeletal and cardiac physiologic and metabolic functions. HS occurs in many diseases such as diabetes mellitus, chronic heart failure, chronic obstructive pulmonary disease, renal and liver failure, trauma, sepsis, and senescence

ceejayoz 1y ago
From https://pubmed.ncbi.nlm.nih.gov/18514619/ https://pubmed.ncbi.nlm.nih.gov/18514619/ ? The bit you left off is pretty telling: > Macronutrients such as [amino acid] supplements, taken together with conventional therapy, may maintain muscular protein metabolism and cell functions. We're right back at "not enough protein".
- tguvot 1y ago
  the other guy wrote "Starvation causes hypercatabolism; it means your body is eating its own proteins. ". this is not case of hypercatabolism as result of starvation. this is one of symptoms of diabetes which "may" could help by "amino acid supplements" so we are not back anywhere.
  - ceejayoz 1y ago
    There is no "other guy". They're both me. > this is not case of hypercatabolism as result of starvation This is an assertion made by the Israeli government, an interested party with a history of lying. "Israel's government denies there is malnutrition in Gaza" is a claim even the Trump administration contests (https://www.bbc.com/news/articles/c62nr9rglm9o https://www.bbc.com/news/articles/c62nr9rglm9o). > this is one of symptoms of diabetes To be clear, they asserted untreated diabetes. Its untreated nature is also something related to the war, Israel having bombed every hospital in Gaza and blockaded all supplies including food. A diabetic's body eating itself in a blockaded war zone with no food or medicine is… unsurprising. Starving people in a slightly roundabout way is still starving people, even if they have existing medical conditions.
    - tguvot 1y ago
      Hypercatabolic syndrome (HS) is a biochemical state characterized by increased circulating catabolic hormones (eg, cortisol, catecholamines) and inflammatory cytokines (eg, tumor necrosis factors, interleukin–1β), and decreased anabolic insulin effects with consequent insulin resistance. nothing to do with starvation. in usa iirc,in usa 20k people died in 2022 or so from malnutrition. were they also in blockaded zone ? or is it just happens so that malnutrition is a complex thing that not always affected by food supply
      - ceejayoz 1y ago
        > increased circulating catabolic hormones AKA stress hormones. I wonder why they're stressed? > nothing to do with starvation. I assure you, if you have one of these conditions, piling starvation on top absolutely hurts your chances of survival. > in usa iirc,in usa 20k people died in 2022 or so from malnutrition. were they also in blockaded zone ? Population-wise, that's the equivalent of 170 in Gaza, and the US numbers are largely elderly people; Gaza is 50% minors. Starvation is the openly stated goal of the Israeli government. https://www.france24.com/en/live-news/20250416-israel-says-no-humanitarian-aid-will-enter-gaza https://www.france24.com/en/live-news/20250416-israel-says-n... > "Israel's policy is clear: no humanitarian aid will enter Gaza, and blocking this aid is one of the main pressure levers preventing Hamas from using it as a tool with the population," [Defense Minister] Katz said in a statement.
        tguvot 1y ago
        Cortisol is a steroid hormone, often referred to as the "stress hormone," that plays a crucial role in regulating various bodily functions and responding to stress. It is produced by the adrenal glands and its release is controlled by the hypothalamic-pituitary-adrenal (HPA) axis. While essential for life, imbalances in cortisol levels can lead to various health issues. adrenal glands disfunction can cause elevated levels of cortisol. adrenal glands also responsible for catecholamines. adrenal glands disfunction can be caused by diabetes, leukamia or number of other conditions. wait till you learn about auto-immune disorders.

by tguvot 1y ago

ceejayoz 1y ago

From https://pubmed.ncbi.nlm.nih.gov/18514619/ https://pubmed.ncbi.nlm.nih.gov/18514619/ ? The bit you left off is pretty telling: > Macronutrients such as [amino acid] supplements, taken together with conventional therapy, may maintain muscular protein metabolism and cell functions. We're right back at "not enough protein".

tguvot 1y ago
the other guy wrote "Starvation causes hypercatabolism; it means your body is eating its own proteins. ". this is not case of hypercatabolism as result of starvation. this is one of symptoms of diabetes which "may" could help by "amino acid supplements" so we are not back anywhere.
- ceejayoz 1y ago
  There is no "other guy". They're both me. > this is not case of hypercatabolism as result of starvation This is an assertion made by the Israeli government, an interested party with a history of lying. "Israel's government denies there is malnutrition in Gaza" is a claim even the Trump administration contests (https://www.bbc.com/news/articles/c62nr9rglm9o https://www.bbc.com/news/articles/c62nr9rglm9o). > this is one of symptoms of diabetes To be clear, they asserted untreated diabetes. Its untreated nature is also something related to the war, Israel having bombed every hospital in Gaza and blockaded all supplies including food. A diabetic's body eating itself in a blockaded war zone with no food or medicine is… unsurprising. Starving people in a slightly roundabout way is still starving people, even if they have existing medical conditions.
  - tguvot 1y ago
    Hypercatabolic syndrome (HS) is a biochemical state characterized by increased circulating catabolic hormones (eg, cortisol, catecholamines) and inflammatory cytokines (eg, tumor necrosis factors, interleukin–1β), and decreased anabolic insulin effects with consequent insulin resistance. nothing to do with starvation. in usa iirc,in usa 20k people died in 2022 or so from malnutrition. were they also in blockaded zone ? or is it just happens so that malnutrition is a complex thing that not always affected by food supply
    - ceejayoz 1y ago
      > increased circulating catabolic hormones AKA stress hormones. I wonder why they're stressed? > nothing to do with starvation. I assure you, if you have one of these conditions, piling starvation on top absolutely hurts your chances of survival. > in usa iirc,in usa 20k people died in 2022 or so from malnutrition. were they also in blockaded zone ? Population-wise, that's the equivalent of 170 in Gaza, and the US numbers are largely elderly people; Gaza is 50% minors. Starvation is the openly stated goal of the Israeli government. https://www.france24.com/en/live-news/20250416-israel-says-no-humanitarian-aid-will-enter-gaza https://www.france24.com/en/live-news/20250416-israel-says-n... > "Israel's policy is clear: no humanitarian aid will enter Gaza, and blocking this aid is one of the main pressure levers preventing Hamas from using it as a tool with the population," [Defense Minister] Katz said in a statement.
      - tguvot 1y ago
        Cortisol is a steroid hormone, often referred to as the "stress hormone," that plays a crucial role in regulating various bodily functions and responding to stress. It is produced by the adrenal glands and its release is controlled by the hypothalamic-pituitary-adrenal (HPA) axis. While essential for life, imbalances in cortisol levels can lead to various health issues. adrenal glands disfunction can cause elevated levels of cortisol. adrenal glands also responsible for catecholamines. adrenal glands disfunction can be caused by diabetes, leukamia or number of other conditions. wait till you learn about auto-immune disorders.