4 ms·

Finally some news regarding this research. I first heard about it back in 2019 when there was an ACS panel featuring it: https://www.youtube.com/live/Dw9D7C8Cp

by Tade0 1y ago

Finally some news regarding this research. I first heard about it back in 2019 when there was an ACS panel featuring it: https://www.youtube.com/live/Dw9D7C8CpM0?si=e-KJ8J2u_oVy4RvM https://www.youtube.com/live/Dw9D7C8CpM0?si=e-KJ8J2u_oVy4RvM Originally there was a mention of developing a less invasive method of correcting a deviated septum, but I guess they went with the harder problem first. In any case I'm up for both, because while my vision is not terrible, it's slowly, but consistently getting worse, so max-twice-a-lifetime interventions like laser eye surgery won't cut it for me.

actionfromafar 1y ago
https://phys.org/news/2019-04-molecular-surgery-reshapes-tissue-electricity.html https://phys.org/news/2019-04-molecular-surgery-reshapes-tis...
stavros 1y ago
Agreed, going from 20/10 vision to "I've given up trying to read small text 50m away" as I age over 40 doesn't affect my quality of life, but it doesn't help my self-esteem.
- jacquesm 1y ago
  I'm between +3 and +4 now depending on how tired I am. I used to be able to read the print on the smallest SMT packages :( And it does affect my quality of life: forget glasses? Good there goes your day until you've found a replacement. The best improvement so far has not been the glasses but a simple string to make sure I don't put them down but they stay around my neck. That has made a massive difference and it also helps when looking down (so the glasses won't fall off) and it has cut the rate at which I was losing them to zero from about one pair per month (which really was not sustainable).
  - stavros 1y ago
    Yeah :( I can still read tiny print, but only for a few seconds, and with a lot of light. Getting old sucks.
    - jacquesm 1y ago
      I got one of these a year ago and it has been a very nice experience so far: https://www.elektor.nl/cdn/shop/files/andonstar-ad409-101-hdmi-digital-microscope19681-447055.jpg https://www.elektor.nl/cdn/shop/files/andonstar-ad409-101-hd... It is also one of those things that you find more and more uses for over time.
      - stavros 1y ago
        Is it really? I tried one of the USB microscopes with a screen, and the lack of depth perception was a massive hindrance when soldering. I solved it with a pair of jeweller's loupes: https://a.aliexpress.com/_EwLf4Sm https://a.aliexpress.com/_EwLf4Sm
        jacquesm 1y ago
        Yes, that took a while to get used to. Jeweller's loupes are an interesting fix, I should try that, thank you.
        stavros 1y ago
        Yes, give it a shot, they are really cheap and give 3D vision. They're great.
      - blackguardx 1y ago
        I'm an EE in my 40s, have 20/20 vision, and never solder without a microscope no matter how large the packages are. The ergonomic advantages are worth it.
        jacquesm 1y ago
        I really only learned to appreciate how useful this is when debugging a PCI express extender cable and seeing the tiniest little solder ball shorting out two wires adjacent to each other.
  - yojo 1y ago
    My in-laws all love their reading glasses with a split-bridge joined by magnets, and a built-in loop around the back. I think it’s these: https://cliceyewear.com/ https://cliceyewear.com/ If you don’t mind the aesthetics (though I personally can’t get past them), they solve the same problem as your string in an integrated way. Plus they rest more like a necklace, since it doesn’t require as long of a loop.
    - jacquesm 1y ago
      That's interesting. I won't be trying them though, I hate frames, it is bad enough with frameless but frames really spoil it for me. One brand in particular that I've found makes glasses that are almost invisible to me when I'm wearing them and that's the one that I've stuck with for the last couple of years. If the tech described here comes to general availability I'll be super happy.
      - jamiek88 1y ago
        Which brand is that? I also hate frames but have a huge head so I’m limited on options!
        jacquesm 1y ago
        I buy them whenever I'm in Latvia, they're called Silac and they're sold in one particular chain of apothecary that I forgot the name of. On the web they are at: https://silac.eu/fr/nos-lunettes/597-643-lunettes-de-lecture-black-metal-5400323709706#/1-dioptrie-125 https://silac.eu/fr/nos-lunettes/597-643-lunettes-de-lecture... But they're quite a bit more expensive online than in the store.
  - pavel_lishin 1y ago
    I usually fold the arms, and hook them over my t-shirt, but they do tend to fall off that way when I bend over. I might have to go with the string approach as well.
    - jacquesm 1y ago
      There is a very painful reason why I stopped doing that.
      - pavel_lishin 1y ago
        Toilet, huh?
        jacquesm 1y ago
        No comment.
  - snozolli 1y ago
    You might want to look into UNR844-Cl. Research was dropped by Novartis, but it's available as a research chemical. https://modernod.com/articles/2020-sept/coming-soon-presbyopia-correcting-eye-drops https://modernod.com/articles/2020-sept/coming-soon-presbyop... (This is assuming your farsightedness is due to age-related presbyopia, hardening of the lens, and not true farsightedness from a change in eyeball shape)
    - Tade0 1y ago
      I had high hopes for this, but according to an executive summary of the last clinical trial: "However, the difference in the eye exam scores after 3 months of taking UNR844-Cl was not large enough to be considered better than placebo, and may have been due to chance." Which is a shame, because it seemed like a great alternative to pilocarpine, which in turn kinda sucks because the only thing it does is create a temporary pinhole effect.
  - vasco 1y ago
    Pro-tip: I you never want to forget your glasses again just make your vision slightly worse! At +4/+5 it's impossible to forget glasses, to the point I forget almost everything yet have not forgotten my glasses a single day of my life since I started using them as a kid.
- Tade0 1y ago
  I remember being able to read the timer on the other end of the subway station(120m) in my city, so in low light conditions at that. The numbers were maybe 20cm in height. In my case it's not even the defect itself, but the associated astigmatism. For a long time I was unaware of the issue because it started in one eye, so the other compensated until it couldn't. Now I get around two weeks of perfect vision upon getting a new glasses prescription and it's back to "normal".

by Tade0 1y ago

actionfromafar 1y ago

https://phys.org/news/2019-04-molecular-surgery-reshapes-tissue-electricity.html https://phys.org/news/2019-04-molecular-surgery-reshapes-tis...

stavros 1y ago

Agreed, going from 20/10 vision to "I've given up trying to read small text 50m away" as I age over 40 doesn't affect my quality of life, but it doesn't help my self-esteem.

jacquesm 1y ago
I'm between +3 and +4 now depending on how tired I am. I used to be able to read the print on the smallest SMT packages :( And it does affect my quality of life: forget glasses? Good there goes your day until you've found a replacement. The best improvement so far has not been the glasses but a simple string to make sure I don't put them down but they stay around my neck. That has made a massive difference and it also helps when looking down (so the glasses won't fall off) and it has cut the rate at which I was losing them to zero from about one pair per month (which really was not sustainable).
- stavros 1y ago
  Yeah :( I can still read tiny print, but only for a few seconds, and with a lot of light. Getting old sucks.
  - jacquesm 1y ago
    I got one of these a year ago and it has been a very nice experience so far: https://www.elektor.nl/cdn/shop/files/andonstar-ad409-101-hdmi-digital-microscope19681-447055.jpg https://www.elektor.nl/cdn/shop/files/andonstar-ad409-101-hd... It is also one of those things that you find more and more uses for over time.
    - stavros 1y ago
      Is it really? I tried one of the USB microscopes with a screen, and the lack of depth perception was a massive hindrance when soldering. I solved it with a pair of jeweller's loupes: https://a.aliexpress.com/_EwLf4Sm https://a.aliexpress.com/_EwLf4Sm
      - jacquesm 1y ago
        Yes, that took a while to get used to. Jeweller's loupes are an interesting fix, I should try that, thank you.
        stavros 1y ago
        Yes, give it a shot, they are really cheap and give 3D vision. They're great.
    - blackguardx 1y ago
      I'm an EE in my 40s, have 20/20 vision, and never solder without a microscope no matter how large the packages are. The ergonomic advantages are worth it.
      - jacquesm 1y ago
        I really only learned to appreciate how useful this is when debugging a PCI express extender cable and seeing the tiniest little solder ball shorting out two wires adjacent to each other.
- yojo 1y ago
  My in-laws all love their reading glasses with a split-bridge joined by magnets, and a built-in loop around the back. I think it’s these: https://cliceyewear.com/ https://cliceyewear.com/ If you don’t mind the aesthetics (though I personally can’t get past them), they solve the same problem as your string in an integrated way. Plus they rest more like a necklace, since it doesn’t require as long of a loop.
  - jacquesm 1y ago
    That's interesting. I won't be trying them though, I hate frames, it is bad enough with frameless but frames really spoil it for me. One brand in particular that I've found makes glasses that are almost invisible to me when I'm wearing them and that's the one that I've stuck with for the last couple of years. If the tech described here comes to general availability I'll be super happy.
    - jamiek88 1y ago
      Which brand is that? I also hate frames but have a huge head so I’m limited on options!
      - jacquesm 1y ago
        I buy them whenever I'm in Latvia, they're called Silac and they're sold in one particular chain of apothecary that I forgot the name of. On the web they are at: https://silac.eu/fr/nos-lunettes/597-643-lunettes-de-lecture-black-metal-5400323709706#/1-dioptrie-125 https://silac.eu/fr/nos-lunettes/597-643-lunettes-de-lecture... But they're quite a bit more expensive online than in the store.
- pavel_lishin 1y ago
  I usually fold the arms, and hook them over my t-shirt, but they do tend to fall off that way when I bend over. I might have to go with the string approach as well.
  - jacquesm 1y ago
    There is a very painful reason why I stopped doing that.
    - pavel_lishin 1y ago
      Toilet, huh?
      - jacquesm 1y ago
        No comment.
- snozolli 1y ago
  You might want to look into UNR844-Cl. Research was dropped by Novartis, but it's available as a research chemical. https://modernod.com/articles/2020-sept/coming-soon-presbyopia-correcting-eye-drops https://modernod.com/articles/2020-sept/coming-soon-presbyop... (This is assuming your farsightedness is due to age-related presbyopia, hardening of the lens, and not true farsightedness from a change in eyeball shape)
  - Tade0 1y ago
    I had high hopes for this, but according to an executive summary of the last clinical trial: "However, the difference in the eye exam scores after 3 months of taking UNR844-Cl was not large enough to be considered better than placebo, and may have been due to chance." Which is a shame, because it seemed like a great alternative to pilocarpine, which in turn kinda sucks because the only thing it does is create a temporary pinhole effect.
- vasco 1y ago
  Pro-tip: I you never want to forget your glasses again just make your vision slightly worse! At +4/+5 it's impossible to forget glasses, to the point I forget almost everything yet have not forgotten my glasses a single day of my life since I started using them as a kid.
Tade0 1y ago
I remember being able to read the timer on the other end of the subway station(120m) in my city, so in low light conditions at that. The numbers were maybe 20cm in height. In my case it's not even the defect itself, but the associated astigmatism. For a long time I was unaware of the issue because it started in one eye, so the other compensated until it couldn't. Now I get around two weeks of perfect vision upon getting a new glasses prescription and it's back to "normal".