The problem with giving a throwaway e-mail address to people you may have a conversation with is that you have the additional hassle of having to use that addre

The problem with giving a throwaway e-mail address to people you may have a conversation with is that you have the additional hassle of having to use that address as your Sender identity when you subsequently reply to their e-mails. Say they write you first. They use your throwaway address. If you just reply to that, you are now using your main address; you have to get your e-mail program to switch to the alternative identity, consistent with the e-mail thread. That's just one more moving part in the scheme requiring configuration. Some mail programs keep sending identities in their own database. You have to create the entry there and then explicitly switch to it when composing an e-mail. To automate that, the throwaway e-mail address system now has to configure your client database in addition to the mail-server-side stuff. Plus your e-mail program has to be patched to select that sender based on an address appearing in the To: or Cc: list of the item you are replying to.