3 ms·
Interestingly, the proposed mechanism seems consistent with the apparent small benefit of anti-amyloid antibody therapy: if amyloid deposits interfere with lith
by amluto 1y ago
Interestingly, the proposed mechanism seems consistent with the apparent small benefit of anti-amyloid antibody therapy: if amyloid deposits interfere with lithium uptake, then removing them could restore some lithium availability without doing anything about the underlying initial cause of insufficient lithium.
- modeless 1y agoWell, it does something about the initial cause of the deficiency, but it doesn't fix the deficiency by itself. Maybe if you took lithium carbonate after clearing the plaques then you would get a recovery. But if just taking lithium orotate instead comprehensively fixes the deficiency regardless of plaques, as it seemed to do in this study, then maybe we don't need to bother treating the plaques at all. Can't wait for human trials!
- cubefox 1y agoUnfortunately lithium orotate can't be patented. It's just a mineral salt. So pharma companies have no incentive to invest in either research or clinical studies.