Obviously the 3D structure of chromosomes are important. But it is only one of many aspects that regulate our genes. While it is true we cannot understand the g

Obviously the 3D structure of chromosomes are important. But it is only one of many aspects that regulate our genes. While it is true we cannot understand the genome by ignoring its 3D shape, we also cannot understand the genome without looking at the many other ways the genome is regulated. Nature did not make things simple for us. There are quite a few variables that regulate our genes, and sadly it seems that all or most of these variables must be taken into account